Owen P McGuinness
Overview
Explore the profile of Owen P McGuinness including associated specialties, affiliations and a list of published articles.
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102
Citations
4745
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Recent Articles
1.
Pittala S, Haspula D, Cui Y, Yang W, Kim Y, Davis R, et al.
Nat Commun
. 2024 Nov;
15(1):9996.
PMID: 39557854
Altered hepatic glucose fluxes are critical during the pathogenesis of type 2 diabetes. G protein-coupled receptors represent important regulators of hepatic glucose production. Recent studies have shown that hepatocytes express...
2.
Laughlin M, McIndoe R, Adams S, Araiza R, Ayala J, Kennedy L, et al.
Mamm Genome
. 2024 Aug;
35(4):485-496.
PMID: 39191872
The Mouse Metabolic Phenotyping Center (MMPC)Live Program was established in 2023 by the National Institute for Diabetes, Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health (NIH) to...
3.
Malabanan E, McGuinness O, Oliver K
Adv Physiol Educ
. 2024 May;
48(3):661-669.
PMID: 38695083
The COVID-19 pandemic and subsequent policies (e.g., social distancing, travel restrictions) challenged both organizers for and attendees of programs typically held in person. Many scientific training programs quickly adapted to...
4.
Winn N, Schleh M, Garcia J, Lantier L, McGuinness O, Blair J, et al.
Mol Metab
. 2024 Feb;
81:101901.
PMID: 38354854
Mammals are protected from changes in environmental temperature by altering energetic processes that modify heat production. Insulin is the dominant stimulus of glucose uptake and metabolism, which are fundamental for...
5.
Weidemann B, Marcheva B, Kobayashi M, Omura C, Newman M, Kobayashi Y, et al.
Cell Metab
. 2024 Jan;
36(1):90-102.e7.
PMID: 38171340
Interactions between lineage-determining and activity-dependent transcription factors determine single-cell identity and function within multicellular tissues through incompletely known mechanisms. By assembling a single-cell atlas of chromatin state within human islets,...
6.
Winn N, Schleh M, Garcia J, Lantier L, McGuinness O, Blair J, et al.
bioRxiv
. 2023 Nov;
PMID: 38014310
Mammals are protected from changes in environmental temperature by altering energetic processes that modify heat production. Insulin is the dominant stimulus of glucose uptake and metabolism, which are fundamental for...
7.
Ceddia R, Zurawski Z, Gray A, Adegboye F, McDonald-Boyer A, Shi F, et al.
J Clin Invest
. 2023 Aug;
133(19).
PMID: 37561580
Negative regulation of exocytosis from secretory cells is accomplished through inhibitory signals from Gi/o GPCRs by Gβγ subunit inhibition of 2 mechanisms: decreased calcium entry and direct interaction of Gβγ...
8.
Vazquez-Borrego M, Del Rio-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, et al.
Metabolism
. 2023 May;
144:155589.
PMID: 37182789
Background: Evidence is accumulating that growth hormone (GH) protects against the development of steatosis and progression of non-alcoholic fatty liver disease (NAFLD). GH may control steatosis indirectly by altering systemic...
9.
Unger C, Aladhami A, Hope 3rd M, Pourhoseini S, Nagarkatti M, McGuinness O, et al.
Sci Rep
. 2022 Oct;
12(1):16668.
PMID: 36198723
Epidemiological literature indicates that women are less susceptible to type II diabetes (T2D) than males. The general consensus is that estrogen is protective, whereas its deficiency in post-menopause is associated...
10.
Ayala J, Lantier L, McGuinness O, Wasserman D
Nat Metab
. 2022 Apr;
4(5):496-498.
PMID: 35477775
No abstract available.