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Sheng-Song Chen

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Articles 16
Citations 97
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Recent Articles
1.
Yu L, Wang Y, Xiao Z, Chen S
Mol Cell Biochem . 2020 Sep; 476(1):187-197. PMID: 32926297
Heat shock protein B8 (HSPB8) impacts on tumor proliferation and migration of malignancy. However, the role of HSPB8 in lung adenocarcinoma (LUAC) remains unclear. The aim of this study, therefore,...
2.
Chen S, Tu X, Xie L, Xiong L, Song J, Ye X
Am J Transl Res . 2018 Oct; 10(9):2940-2948. PMID: 30323880
Acquired resistance to chemotherapy is a major limitation for the successful treatment of lung cancer. Previously, we and others showed that formation of tumor spheres is associated with chemotherapy resistance...
3.
Chen S, Zhou H, Tong B, Yu L, Fan S, Xiao Z
Medicine (Baltimore) . 2017 Dec; 96(49):e9085. PMID: 29245328
Rationale: Endobronchial hamartoma, the most common benign lung tumor, is located in the bronchus, and it easily mimics lung cancer or bronchial metastasis. Endobronchial hamartoma can cause coughing, hemoptysis, and...
4.
Xie L, Sun F, He B, Zhan X, Song J, Chen S, et al.
Tumour Biol . 2015 Nov; 37(4):4929-37. PMID: 26526583
The presence of cancer stem cells (CSCs) is the source of occurrence, aggravation, and recurrence of lung cancer. Accordingly, targeting killing the lung CSCs has been suggested to be an...
5.
Chen S, Song J, Tu X, Zhao J, Ye X
Int J Clin Exp Med . 2015 Sep; 8(7):10845-54. PMID: 26379878
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases responsible for degrading essentially all components of the extracellular matrix (ECM). Accumulating evidence suggests that MMPs might play a critical role...
6.
Sun F, Hu Y, Xiong L, Tu X, Zhao J, Chen S, et al.
Int J Clin Exp Pathol . 2015 Aug; 8(6):6287-300. PMID: 26261505
There is growing evidence suggesting that cancer stem cells (CSCs) are playing critical roles in tumor progression, metastasis and drug resistance. However, the role of CSCs in non-small cell lung...
7.
Chen S, Otero Y, Mulligan K, Lundblad T, Williams P, McGuinness O
PLoS One . 2014 Jan; 9(1):e86164. PMID: 24465939
Hyperglycemia in the hospitalized setting is common, especially in patients that receive nutritional support either continuously or intermittently. As the liver and muscle are the major sites of glucose disposal,...
8.
Johnson P, Chen S, Santomango T, Williams P, Lacy D, McGuinness O
Metabolism . 2010 Oct; 60(6):867-73. PMID: 20940071
An adaptation to continuous total parenteral nutrition (TPN; 75% of nonprotein calories as glucose) is the liver becomes a major consumer of glucose with lactate release as a by-product. The...
9.
Chen S, Santomango T, Williams P, Lacy D, McGuinness O
Am J Physiol Endocrinol Metab . 2009 Feb; 296(5):E1172-8. PMID: 19208853
Glucose, fat, and glucagon availability are increased in diabetes. The normal response of the liver to chronic increases in glucose availability is to adapt to become a marked consumer of...
10.
Chen S, Zhang Y, Santomango T, Williams P, Lacy D, McGuinness O
Am J Physiol Endocrinol Metab . 2006 Nov; 292(3):E928-35. PMID: 17132827
Defects in insulin secretion and/or action contribute to the hyperglycemia of stressed and diabetic patients, and we hypothesize that failure to suppress glucagon also plays a role. We examined the...