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Olivier Gires

Explore the profile of Olivier Gires including associated specialties, affiliations and a list of published articles. Areas
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Articles 96
Citations 2972
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Recent Articles
1.
Ourailidis I, Stogbauer F, Zhou Y, Beck S, Romanovsky E, Eckert S, et al.
NPJ Precis Oncol . 2025 Mar; 9(1):73. PMID: 40082664
Tumor budding (TB) is a prognostic biomarker in HPV-negative and HPV-positive head and neck squamous cell carcinoma (HNSCC). Analyzing TCGA and CPTAC mutation, RNA, and RPPA data and performing proteomics...
2.
Kellner M, Hormann J, Fackler S, Hu Y, Zhou T, Lu L, et al.
Cells . 2024 Sep; 13(18. PMID: 39329747
The membrane composition of extracellular vesicles (EVs) largely reflects that of the plasma membrane of the cell of origin. We therefore hypothesized that EVs could be used for immunizations to...
3.
Xu G, Huang R, Wumaier R, Lyu J, Huang M, Zhang Y, et al.
Cancer Res . 2024 Jun; 84(19):3267-3285. PMID: 38900939
Analysis of extracellular vesicles (EV) is a promising noninvasive liquid biopsy approach for breast cancer detection, prognosis, and therapeutic monitoring. A comprehensive understanding of the characteristics and proteomic composition of...
4.
Danko B, Hess J, Unger K, Samaga D, Walz C, Walch A, et al.
NPJ Precis Oncol . 2024 May; 8(1):116. PMID: 38783045
Head and Neck Squamous Cell Carcinoma (HNSCC) is a heterogeneous malignancy that remains a significant challenge in clinical management due to frequent treatment failures and pronounced therapy resistance. While metabolic...
5.
Fan G, Yu B, Tang L, Zhu R, Chen J, Zhu Y, et al.
Sci Transl Med . 2024 Apr; 16(741):eadj5705. PMID: 38569015
Cancer-associated fibroblasts (CAFs) are abundant stromal cells in the tumor microenvironment that promote cancer progression and relapse. However, the heterogeneity and regulatory roles of CAFs underlying chemoresistance remain largely unclear....
6.
Stocker M, Blancke Soares A, Liebsch G, Meier R, Canis M, Gires O, et al.
Front Oncol . 2024 Feb; 14:1002798. PMID: 38390268
Introduction: Head and neck squamous cell carcinoma (HNSCC) patients suffer from frequent local recurrences that negatively impact on prognosis. Hence, distinguishing tumor and normal tissue is of clinical importance as...
7.
Broghammer F, Korovina I, Gouda M, Celotti M, van Es J, Lange I, et al.
Mol Cancer . 2024 Feb; 23(1):39. PMID: 38378518
Background: Focal adhesion signaling involving receptor tyrosine kinases (RTK) and integrins co-controls cancer cell survival and therapy resistance. However, co-dependencies between these receptors and therapeutically exploitable vulnerabilities remain largely elusive...
8.
Shi E, Wu Z, Karaoglan B, Schwenk-Zieger S, Kranz G, Abdul Razak N, et al.
J Biomed Sci . 2023 Aug; 30(1):72. PMID: 37620936
Background: Epithelial-to-mesenchymal transition (EMT) of malignant cells is a driving force of disease progression in human papillomavirus-negative (HPV-negative) head and neck squamous cell carcinomas (HNSCC). Sustained hyper-activation of epidermal growth...
9.
Wang Y, Zhang L, Tan J, Zhang Z, Liu Y, Hu X, et al.
Cancer Lett . 2023 Aug; 571:216337. PMID: 37553013
Current management of small cell lung cancer (SCLC) remains challenging. Effective biomarkers are needed to subdivide patients presenting distinct treatment response and clinical outcomes. An understanding of heterogeneous phenotypes of...
10.
He M, Gouda M, Gires O
Oral Oncol . 2023 Jun; 143:106465. PMID: 37348447
No abstract available.