Olivier Diaz
Overview
Explore the profile of Olivier Diaz including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
654
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Recent Articles
1.
Jacquemin C, El Orch W, Diaz O, Lalande A, Aublin-Gex A, Jacolin F, et al.
Cell Mol Life Sci
. 2024 Jul;
81(1):320.
PMID: 39078527
The hypoxia response pathway enables adaptation to oxygen deprivation. It is mediated by hypoxia-inducible factors (HIF), which promote metabolic reprogramming, erythropoiesis, angiogenesis and tissue remodeling. This led to the successful...
2.
Ogire E, Perrin-Cocon L, Figl M, Kundlacz C, Jacquemin C, Hubert S, et al.
Antiviral Res
. 2024 Jun;
228:105939.
PMID: 38909960
Viruses have developed sophisticated strategies to control metabolic activity of infected cells in order to supply replication machinery with energy and metabolites. Dengue virus (DENV), a mosquito-borne flavivirus responsible for...
3.
Aublin-Gex A, Jacolin F, Diaz O, Jacquemin C, Marcais A, Walzer T, et al.
Eur J Immunol
. 2024 Jun;
54(9):e2350954.
PMID: 38837415
Hexokinases (HKs) control the first step of glucose catabolism. A switch of expression from liver HK (glucokinase, GCK) to the tumor isoenzyme HK2 is observed in hepatocellular carcinoma progression. Our...
4.
Diaz O, Legrand A, El-Orch W, Jacolin F, Lotteau V, Ramiere C, et al.
Med Sci (Paris)
. 2023 Nov;
39(10):754-762.
PMID: 37943136
Hepatitis viruses modify the cellular metabolism of hepatocytes by interacting with specific enzymes such as glucokinase. The metabolic changes induced by viruses can have a direct impact on the innate...
5.
Diaz O, Vidalain P, Ramiere C, Lotteau V, Perrin-Cocon L
Front Immunol
. 2022 Dec;
13:1033314.
PMID: 36466918
Hepatitis B, C and D viruses (HBV, HCV, HDV, respectively) specifically infect human hepatocytes and often establish chronic viral infections of the liver, thus escaping antiviral immunity for years. Like...
6.
Perrin-Cocon L, Kundlacz C, Jacquemin C, Hanoulle X, Aublin-Gex A, Figl M, et al.
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35055105
Hepatitis C virus (HCV) relies on cellular lipid metabolism for its replication, and actively modulates lipogenesis and lipid trafficking in infected hepatocytes. This translates into an intracellular accumulation of triglycerides...
7.
Ogire E, Diaz O, Vidalain P, Lotteau V, Despres P, Roche M
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33669407
La Reunion island in the South West Indian Ocean is now endemic for dengue following the introduction of dengue virus serotype 2 (DENV-2) cosmopolitan-I genotype in 2017. DENV-2 infection causes...
8.
Perrin-Cocon L, Vidalain P, Jacquemin C, Aublin-Gex A, Olmstead K, Panthu B, et al.
Commun Biol
. 2021 Feb;
4(1):217.
PMID: 33594203
During the cancerous transformation of normal hepatocytes into hepatocellular carcinoma (HCC), the enzyme catalyzing the first rate-limiting step of glycolysis, namely the glucokinase (GCK), is replaced by the higher affinity...
9.
Perrin-Cocon L, Diaz O, Jacquemin C, Barthel V, Ogire E, Ramiere C, et al.
J Transl Med
. 2020 Aug;
18(1):319.
PMID: 32811513
In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, have emerged in human population causing hundreds to hundreds of thousands of deaths. Other coronaviruses are causing epizootic...
10.
Hayek S, Pietrancosta N, Hovhannisyan A, Alves de Sousa R, Bekaddour N, Ermellino L, et al.
Eur J Med Chem
. 2019 Nov;
186:111855.
PMID: 31740051
There is an increasing interest in the field of cancer therapy for small compounds targeting pyrimidine biosynthesis, and in particular dihydroorotate dehydrogenase (DHODH), the fourth enzyme of this metabolic pathway....