Patrice Andre
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Explore the profile of Patrice Andre including associated specialties, affiliations and a list of published articles.
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Articles
98
Citations
2386
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Recent Articles
1.
Meyniel-Schicklin L, Amaudrut J, Mallinjoud P, Guillier F, Mangeot P, Lines L, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(5):e2308776121.
PMID: 38252831
We present a drug design strategy based on structural knowledge of protein-protein interfaces selected through virus-host coevolution and translated into highly potential small molecules. This approach is grounded on Vinland,...
2.
Legrand A, Lucifora J, Lacombe B, Menard C, Michelet M, Foca A, et al.
Hepatol Commun
. 2023 Apr;
7(5).
PMID: 37058078
Background And Aims: HDV, a satellite of HBV, is responsible for the most severe form of human viral hepatitis, for which curative therapy is still awaited. Both HBV and HDV...
3.
Perrin-Cocon L, Kundlacz C, Jacquemin C, Hanoulle X, Aublin-Gex A, Figl M, et al.
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35055105
Hepatitis C virus (HCV) relies on cellular lipid metabolism for its replication, and actively modulates lipogenesis and lipid trafficking in infected hepatocytes. This translates into an intracellular accumulation of triglycerides...
4.
Mathieu C, Touret F, Jacquemin C, Janin Y, Nougairede A, Brailly M, et al.
Viruses
. 2021 Sep;
13(9).
PMID: 34578395
Our therapeutic arsenal against viruses is very limited and the current pandemic of SARS-CoV-2 highlights the critical need for effective antivirals against emerging coronaviruses. Cellular assays allowing a precise quantification...
5.
Erken R, Andre P, Roy E, Kootstra N, Barzic N, Girma H, et al.
J Viral Hepat
. 2021 Sep;
28(12):1690-1698.
PMID: 34467593
The nuclear farnesoid X receptor (FXR) regulates bile acid homeostasis and is a drug target for metabolic liver diseases. FXR also plays an important role in hepatitis B virus (HBV)...
6.
Perrin-Cocon L, Vidalain P, Jacquemin C, Aublin-Gex A, Olmstead K, Panthu B, et al.
Commun Biol
. 2021 Feb;
4(1):217.
PMID: 33594203
During the cancerous transformation of normal hepatocytes into hepatocellular carcinoma (HCC), the enzyme catalyzing the first rate-limiting step of glycolysis, namely the glucokinase (GCK), is replaced by the higher affinity...
7.
Perrin-Cocon L, Diaz O, Jacquemin C, Barthel V, Ogire E, Ramiere C, et al.
J Transl Med
. 2020 Aug;
18(1):319.
PMID: 32811513
In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, have emerged in human population causing hundreds to hundreds of thousands of deaths. Other coronaviruses are causing epizootic...
8.
Mouzannar K, Fusil F, Lacombe B, Ollivier A, Menard C, Lotteau V, et al.
FASEB J
. 2018 Oct;
33(2):2472-2483.
PMID: 30307769
Hepatitis B virus (HBV) infection and bile acid (BA) metabolism are interdependent: infection modifies the expression of the BA nuclear receptor farnesoid X receptor (FXR)-α, and modulation of FXRα activity...
9.
Perrin-Cocon L, Aublin-Gex A, Diaz O, Ramiere C, Peri F, Andre P, et al.
J Immunol
. 2018 Jul;
201(5):1510-1521.
PMID: 30037846
Cell metabolism now appears as an essential regulator of immune cells activation. In particular, TLR stimulation triggers metabolic reprogramming of dendritic cells (DCs) with an increased glycolytic flux, whereas inhibition...
10.
Vandevoorde K, Ducreux S, Bosch A, Guillaud O, Hervieu V, Chambon-Augoyard C, et al.
Liver Transpl
. 2018 Apr;
24(8):1091-1100.
PMID: 29665189
The incidence and impact of anti-human leukocyte antigen donor-specific alloantibodies (DSAs) developing after liver transplantation (LT) remains controversial and not extensively studied. The aim of the present study was to...