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Oliver Bannard

Explore the profile of Oliver Bannard including associated specialties, affiliations and a list of published articles. Areas
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Citations 917
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Recent Articles
1.
Sprumont A, Rodrigues A, McGowan S, Bannard C, Bannard O
Cell . 2023 Nov; 186(25):5486-5499.e13. PMID: 37951212
Germinal centers (GCs) form in lymph nodes after immunization or infection to facilitate antibody affinity maturation and memory and plasma cell (PC) development. PC differentiation is thought to involve stringent...
2.
Grootveld A, Kyaw W, Panova V, Lau A, Ashwin E, Seuzaret G, et al.
Cell . 2023 Mar; 186(6):1144-1161.e18. PMID: 36868219
Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary...
3.
MacLean A, Richmond N, Koneva L, Attar M, Medina C, Thornton E, et al.
Immunity . 2022 Mar; 55(4):718-733.e8. PMID: 35349789
Resident memory B (BRM) cells develop and persist in the lungs of influenza-infected mice and humans; however, their contribution to recall responses has not been defined. Here, we used two-photon...
4.
Long Z, Phillips B, Radtke D, Meyer-Hermann M, Bannard O
Sci Immunol . 2022 Mar; 7(69):eabm0775. PMID: 35275753
Antibody affinity maturation occurs in germinal centers (GCs) through iterative rounds of somatic hypermutation and proliferation in dark zones (DZs) and selection in light zones (LZs). GC B cells exit...
5.
Frost J, Tan T, Abbas M, Wideman S, Bonadonna M, Stoffel N, et al.
Med . 2021 Mar; 2(2):164-179.e12. PMID: 33665641
Background: How specific nutrients influence adaptive immunity is of broad interest. Iron deficiency is the most common micronutrient deficiency worldwide and imparts a significant burden of global disease; however, its...
6.
Bannard O
Immunity . 2019 Sep; 51(3):420-423. PMID: 31533053
The genes encoding the histone acetyltransferases (HATs) CREBB-binding protein (CREBBP) and EP300 are commonly mutated in germinal-center-derived B cell lymphomas, and their inactivation is thought to contribute to lymphomagenesis. In...
7.
Radtke D, Bannard O
Front Immunol . 2019 Jan; 9:3106. PMID: 30687317
Long-lived plasma cells (PCs) develop in germinal centers (GCs) by the differentiation of affinity matured B cells. Antibody affinity maturation involves iterative rounds of somatic hypermutation in dark zones (DZs)...
8.
Stewart I, Radtke D, Phillips B, McGowan S, Bannard O
Immunity . 2018 Sep; 49(3):477-489.e7. PMID: 30231983
Adaptive immunity involves the development of bespoke antibodies in germinal centers (GCs) through immunoglobulin somatic hypermutation (SHM) in GC dark zones (DZs) and clonal selection in light zones (LZs). Accurate...
9.
Bannard O, Cyster J
Curr Opin Immunol . 2017 Jan; 45:21-30. PMID: 28088708
The seminal discovery by Eisen that antibodies undergo improvements in antigen-binding affinity over the course of an immune response led to a long running search for the underlying mechanism. Germinal...
10.
Bannard O, McGowan S, Ersching J, Ishido S, Victora G, Shin J, et al.
J Exp Med . 2016 May; 213(6):993-1009. PMID: 27162138
Antibody affinity maturation occurs in germinal centers (GCs) through iterative rounds of somatic hypermutation and selection. Selection involves B cells competing for T cell help based on the amount of...