Tiong Kit Tan
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Explore the profile of Tiong Kit Tan including associated specialties, affiliations and a list of published articles.
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41
Citations
2358
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Recent Articles
1.
Sadler H, Rijal P, Tan T, Townsend A
J Virol
. 2025 Jan;
99(2):e0033124.
PMID: 39868800
Importance: Influenza is a serious public health concern, causing seasonal epidemics as well as pandemics in people. Influenza can also cause severe agricultural losses due to its circulation in farmed...
2.
Huhn A, Nissley D, Wilson D, Kutuzov M, Donat R, Tan T, et al.
Nat Commun
. 2025 Jan;
16(1):338.
PMID: 39746910
Key functions of antibodies, such as viral neutralisation, depend on high-affinity binding. However, viral neutralisation poorly correlates with antigen affinity for reasons that have been unclear. Here, we use a...
3.
Cheow P, Tan T, Song A, Yusoff K, Chia S
Avian Pathol
. 2024 Sep;
54(1):149-157.
PMID: 39318350
Development of nr-NDV.Reverse transfection was applied for the recovery of nr-NDV.Propagation of nr-NDV was done by sub-passaging transfected BSR T7/5 cells.Safety profile was done to prove that the nr-NDV is...
4.
Chen X, Mohapatra A, Nguyen H, Schimanski L, Tan T, Rijal P, et al.
PLoS Pathog
. 2024 Jun;
20(6):e1012246.
PMID: 38857264
Antibody-mediated immunity plays a key role in protection against SARS-CoV-2. We characterized B-cell-derived anti-SARS-CoV-2 RBD antibody repertoires from vaccinated and infected individuals and elucidate the mechanism of action of broadly...
5.
Hills R, Tan T, Cohen A, Keeffe J, Keeble A, Gnanapragasam P, et al.
Nat Nanotechnol
. 2024 May;
19(8):1216-1223.
PMID: 38710880
Defending against future pandemics requires vaccine platforms that protect across a range of related pathogens. Nanoscale patterning can be used to address this issue. Here, we produce quartets of linked...
6.
Rahikainen R, Rijal P, Tan T, Wu H, Andersson A, Barrett J, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
133(1):325-334.
PMID: 38504824
Matching of symmetry at interfaces is a fundamental obstacle in molecular assembly. Virus-like particles (VLPs) are important vaccine platforms against pathogenic threats, including Covid-19. However, symmetry mismatch can prohibit vaccine...
7.
Zheng M, Tan T, Villalon-Letelier F, Lau H, Deng Y, Fritzlar S, et al.
Sci Adv
. 2023 Sep;
9(36):eadg3469.
PMID: 37683004
Influenza virus-specific tissue-resident memory (Trm) CD8 T cells located along the respiratory tract provide cross-strain protection against a breadth of influenza viruses. We show that immunization with a single-cycle influenza...
8.
Hills R, Tan T, Cohen A, Keeffe J, Keeble A, Gnanapragasam P, et al.
bioRxiv
. 2023 Mar;
PMID: 36865256
Defending against future pandemics may require vaccine platforms that protect across a range of related pathogens. The presentation of multiple receptor-binding domains (RBDs) from evolutionarily-related viruses on a nanoparticle scaffold...
9.
Gelinas A, Tan T, Liu S, Jaramillo J, Chadwick J, Harding A, et al.
Mol Ther Nucleic Acids
. 2023 Jan;
31:370-382.
PMID: 36714461
Since its discovery, COVID-19 has rapidly spread across the globe and has had a massive toll on human health, with infection mortality rates as high as 10%, and a crippling...
10.
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
Huang K, Chen X, Mohapatra A, Nguyen H, Schimanski L, Tan T, et al.
Nat Commun
. 2023 Jan;
14(1):311.
PMID: 36658148
Antibody-mediated immunity plays a crucial role in protection against SARS-CoV-2 infection. We isolated a panel of neutralizing anti-receptor-binding domain (RBD) antibodies elicited upon natural infection and vaccination and showed that...