Daniel Radtke
Overview
Explore the profile of Daniel Radtke including associated specialties, affiliations and a list of published articles.
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19
Citations
238
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Recent Articles
1.
Westermann S, Radtke D, Kramer L, Wirtz S, Voehringer D
Eur J Immunol
. 2024 Dec;
55(2):e202451394.
PMID: 39670708
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) often associated with a Type 2 immune response. Although previous reports hint at a role for signal transducer and activator of...
2.
Ruhl A, Vieira Antao A, Dietschmann A, Radtke D, Tenbusch M, Voehringer D
Eur J Immunol
. 2023 Oct;
54(1):e2350558.
PMID: 37855177
Airway epithelial cells contribute to a variety of lung diseases including allergic asthma, where IL-4 and IL-13 promote activation of the transcription factor STAT6. This leads to goblet cell hyperplasia...
3.
Satzinger S, Willenborg S, Ding X, Klose C, Radtke D, Voehringer D, et al.
J Invest Dermatol
. 2023 Jun;
143(12):2456-2467.e5.
PMID: 37295491
Type 2 immune responses have been increasingly linked with tissue maintenance, regeneration, and metabolic homeostasis. The molecular basis of regulator and effector mechanisms of type 2 immunity in skin regeneration...
4.
Westermann S, Schubart C, Dietschmann A, Castiglione K, Radtke D, Voehringer D
PLoS Pathog
. 2023 Apr;
19(4):e1011296.
PMID: 37018382
Gastrointestinal helminths are a major health threat worldwide. Alternatively activated macrophages (AAMs) have been shown to contribute to host protection during secondary helminth infections. AAMs express effector molecules that depend...
5.
Radtke D, Voehringer D
Eur J Immunol
. 2023 Mar;
53(8):e2249977.
PMID: 36929502
Granulocytes provide a fast innate response to pathogens and allergens. In allergy and anti-helminth immunity, epithelial cells of damaged barriers release alarmins like IL-25, IL-33, and thymic stromal lymphopoietin (TSLP)...
6.
Thuma N, Dohler D, Mielenz D, Sticht H, Radtke D, Reimann L, et al.
Front Immunol
. 2022 Sep;
13:979491.
PMID: 36091065
Hookworms infect more that 400 million people and cause significant socio-economic burden on endemic countries. The lack of efficient vaccines and the emergence of anthelminthic drug resistance are of major...
7.
Radtke D, Thuma N, Schulein C, Kirchner P, Ekici A, Schober K, et al.
Elife
. 2022 Aug;
11.
PMID: 35950748
Th2 cells provide effector functions in type 2 immune responses to helminths and allergens. Despite knowledge about molecular mechanisms of Th2 cell differentiation, there is little information on Th2 cell...
8.
Dietschmann A, Schruefer S, Westermann S, Henkel F, Castiglione K, Willebrand R, et al.
mBio
. 2022 Jun;
13(4):e0123922.
PMID: 35695427
Eosinophilia is associated with various persisting inflammatory diseases and often coincides with chronic fungal infections or fungal allergy as in the case of allergic bronchopulmonary aspergillosis (ABPA). Here, we show...
9.
Long Z, Phillips B, Radtke D, Meyer-Hermann M, Bannard O
Sci Immunol
. 2022 Mar;
7(69):eabm0775.
PMID: 35275753
Antibody affinity maturation occurs in germinal centers (GCs) through iterative rounds of somatic hypermutation and proliferation in dark zones (DZs) and selection in light zones (LZs). GC B cells exit...
10.
Westermann S, Dietschmann A, Doehler D, Castiglione K, Bochner B, Voehringer D, et al.
J Immunol
. 2022 Jan;
208(3):732-744.
PMID: 34996839
Eosinophils are potent innate effector cells associated mainly with type 2 immune responses elicited by helminths and allergens. Their activity needs to be tightly controlled to prevent severe inflammation and...