Oleg Fedorov
Overview
Explore the profile of Oleg Fedorov including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
107
Citations
6000
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Korneenko E, Rog I, Chudinov I, Lukina-Gronskaya A, Kozyreva A, Belyaletdinova I, et al.
BMC Infect Dis
. 2025 Mar;
25(1):363.
PMID: 40089690
Background: Mycoplasma pneumoniae (MP) is a common bacterial respiratory infection that can cause pneumonia, particularly in children. Previously published data have highlighted the high incidence of viral co-infections and the...
2.
Grosjean H, Aimon A, Hassell-Hart S, Thompson W, Koekemoer L, Bennett J, et al.
Angew Chem Int Ed Engl
. 2025 Feb;
:e202424373.
PMID: 39931803
Fragment approaches are long-established in target-based ligand discovery yet their full transformative potential lies dormant, because progressing hits to potency remains underserved by methodological work. The only credible progression paradigm...
3.
Sumarokova M, Pavlov R, Lavushchenko T, Vasilenko E, Kozhemyakin G, Fedorov O, et al.
Int J Mol Sci
. 2025 Jan;
26(2).
PMID: 39859399
SARS-CoV-2 viral entry requires membrane fusion, which is facilitated by the fusion peptides within its spike protein. These predominantly hydrophobic peptides insert into target membranes; however, their precise mechanistic role...
4.
Giroud C, Szommer T, Coxon C, Monteiro O, Grimes T, Zarganes-Tzitzikas T, et al.
J Med Chem
. 2024 Oct;
67(21):18943-18956.
PMID: 39425667
The S100 protein family functions as protein-protein interaction adaptors regulated by Ca binding. Formation of various S100 complexes plays a central role in cell functions, from calcium homeostasis to cell...
5.
Balikci E, Marques A, Bauer L, Seupel R, Bennett J, Raux B, et al.
J Med Chem
. 2024 Apr;
67(9):7245-7259.
PMID: 38635563
Cofactor mimicry represents an attractive strategy for the development of enzyme inhibitors but can lead to off-target effects due to the evolutionary conservation of binding sites across the proteome. Here,...
6.
Xiong Y, Greschik H, Johansson C, Seifert L, Gamble V, Park K, et al.
J Med Chem
. 2024 Mar;
67(7):5837-5853.
PMID: 38533580
The methyl-lysine reader protein SPIN1 plays important roles in various human diseases. However, targeting methyl-lysine reader proteins has been challenging. Very few cellularly active SPIN1 inhibitors have been developed. We...
7.
Henderson S, Sorrell F, Bennett J, Fedorov O, Hanley M, Godoi P, et al.
Eur J Med Chem
. 2024 Mar;
269():116292.
PMID: 38479168
Selective inhibitors of DYRK1A are of interest for the treatment of cancer, Type 2 diabetes and neurological disorders. Optimization of imidazo [1,2-b]pyridazine fragment 1 through structure-activity relationship exploration and in...
8.
Raux B, Buchan K, Bennett J, Christott T, Dowling M, Farnie G, et al.
Bioorg Med Chem Lett
. 2023 Nov;
98:129546.
PMID: 37944866
Epigenetic proteins containing YEATS domains (YD) are an emerging target class in drug discovery. Described herein are the discovery and characterization efforts associated with PFI-6, a new chemical probe for...
9.
Boby M, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson M, et al.
Science
. 2023 Nov;
382(6671):eabo7201.
PMID: 37943932
We report the results of the COVID Moonshot, a fully open-science, crowdsourced, and structure-enabled drug discovery campaign targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease. We discovered...
10.
Schuller M, Zarganes-Tzitzikas T, Bennett J, De Cesco S, Fearon D, von Delft F, et al.
Pathogens
. 2023 Feb;
12(2).
PMID: 36839595
The worldwide public health and socioeconomic consequences caused by the COVID-19 pandemic highlight the importance of increasing preparedness for viral disease outbreaks by providing rapid disease prevention and treatment strategies....