Oksana Horyn
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Explore the profile of Oksana Horyn including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
578
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Recent Articles
11.
Falfushynska H, Horyn O, Brzozowska A, Fedoruk O, Buyak B, Poznansky D, et al.
Aquat Toxicol
. 2018 Nov;
206:105-113.
PMID: 30472479
As yet European strains of Raphidiopsis raciborskii (previously Cylindrospermopsis raciborskii) have not been found to produce known cyanotoxins although their extracts have caused adverse effects in mammals, as shown using...
12.
Rzymski P, Horyn O, Budzynska A, Jurczak T, Kokocinski M, Niedzielski P, et al.
Environ Sci Pollut Res Int
. 2018 Apr;
25(15):15245-15252.
PMID: 29680888
The occurrence of cyanobacteria in freshwaters attracts much attention due to its associated health threats and ecological implications. Yet data on the composition of cyanobacteria taxa and toxigenicity in some...
13.
Falfushynska H, Gnatyshyna L, Horyn O, Stoliar O
Comp Biochem Physiol C Toxicol Pharmacol
. 2017 Aug;
202:26-38.
PMID: 28757214
Pharmaceutical and personal care products (PPCPs) are the environmental pollutants of growing concern. The aim of this study was to indicate the effects of typical PPCPs on the marsh frog...
14.
Falfushynska H, Gnatyshyna L, Horyn O, Sokolova I, Stoliar O
Aquat Toxicol
. 2017 Feb;
185:171-182.
PMID: 28226256
Freshwater organisms including amphibians experience increasing exposures to emerging pollutants such as nanoparticles and pharmaceuticals, which can affect their fitness and performance. We studied the effects of two common pollutants...
15.
Raju K, Doulias P, Evans P, Krizman E, Jackson J, Horyn O, et al.
Sci Signal
. 2015 Jul;
8(384):ra68.
PMID: 26152695
Nitric oxide (NO) is a signaling intermediate during glutamatergic neurotransmission in the central nervous system (CNS). NO signaling is in part accomplished through cysteine S-nitrosylation, a posttranslational modification by which...
16.
Nissim I, Horyn O, Daikhin Y, Chen P, Li C, Wehrli S, et al.
J Biol Chem
. 2014 Feb;
289(14):9710-29.
PMID: 24523404
Agmatine (AGM), a product of arginine decarboxylation, influences multiple physiologic and metabolic functions. However, the mechanism(s) of action, the impact on whole body gene expression and metabolic pathways, and the...
17.
Nissim I, Horyn O, Nissim I, Daikhin Y, Wehrli S, Yudkoff M, et al.
Biochem J
. 2012 Mar;
444(3):537-51.
PMID: 22448977
GKAs (glucokinase activators) are promising agents for the therapy of Type 2 diabetes, but little is known about their effects on hepatic intermediary metabolism. We monitored the fate of (13)C-labelled...
18.
Falk M, Polyak E, Zhang Z, Peng M, King R, Maltzman J, et al.
EMBO Mol Med
. 2011 May;
3(7):410-27.
PMID: 21567994
Therapy of mitochondrial respiratory chain diseases is complicated by limited understanding of cellular mechanisms that cause the widely variable clinical findings. Here, we show that focal segmental glomerulopathy-like kidney disease...
19.
Nissim I, Horyn O, Nissim I, Daikhin Y, Caldovic L, Barcelona B, et al.
J Biol Chem
. 2011 May;
286(25):22055-68.
PMID: 21540182
We previously reported that isobutylmethylxanthine (IBMX), a derivative of oxypurine, inhibits citrulline synthesis by an as yet unknown mechanism. Here, we demonstrate that IBMX and other oxypurines containing a 2,6-dione...
20.
Yudkoff M, Mew N, Daikhin Y, Horyn O, Nissim I, Nissim I, et al.
Mol Genet Metab
. 2010 Mar;
100 Suppl 1:S37-41.
PMID: 20338795
Stable isotopes have been an invaluable adjunct to biomedical research for more than 70years. Indeed, the isotopic approach has revolutionized our understanding of metabolism, revealing it to be an intensely...