Oakley C Olson
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Explore the profile of Oakley C Olson including associated specialties, affiliations and a list of published articles.
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17
Citations
2626
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Recent Articles
1.
Swann J, Olson O, Passegue E
Nat Rev Immunol
. 2024 Mar;
24(8):596-613.
PMID: 38467802
Definitive haematopoiesis is the process by which haematopoietic stem cells, located in the bone marrow, generate all haematopoietic cell lineages in healthy adults. Although highly regulated to maintain a stable...
2.
LaMarche N, Hegde S, Park M, Maier B, Troncoso L, Le Berichel J, et al.
Nature
. 2023 Dec;
625(7993):166-174.
PMID: 38057662
Myeloid cells are known to suppress antitumour immunity. However, the molecular drivers of immunosuppressive myeloid cell states are not well defined. Here we used single-cell RNA sequencing of human and...
3.
Kang Y, Paik H, Zhang S, Chen J, Olson O, Mitchell C, et al.
J Exp Med
. 2023 Apr;
220(8).
PMID: 37115584
Hematopoietic stem cells (HSC) and downstream lineage-biased multipotent progenitors (MPP) tailor blood production and control myelopoiesis on demand. Recent lineage tracing analyses revealed MPPs to be major functional contributors to...
4.
Mitchell C, Verovskaya E, Calero-Nieto F, Olson O, Swann J, Wang X, et al.
Nat Cell Biol
. 2023 Jan;
25(1):30-41.
PMID: 36650381
Haematopoietic ageing is marked by a loss of regenerative capacity and skewed differentiation from haematopoietic stem cells (HSCs), leading to impaired blood production. Signals from the bone marrow niche tailor...
5.
Yamashita M, Dellorusso P, Olson O, Passegue E
Nat Rev Cancer
. 2020 May;
20(7):365-382.
PMID: 32415283
Haematopoiesis is governed by haematopoietic stem cells (HSCs) that produce all lineages of blood and immune cells. The maintenance of blood homeostasis requires a dynamic response of HSCs to stress,...
6.
Olson O, Kang Y, Passegue E
Cold Spring Harb Perspect Med
. 2020 Jan;
10(12).
PMID: 31988205
The hematopoietic system is highly organized to maintain its functional integrity and to meet lifelong organismal demands. Hematopoietic stem cells (HSCs) must balance self-renewal with differentiation and the regeneration of...
7.
Olson O, Quail D, Joyce J
Science
. 2017 Dec;
358(6367):1130-1131.
PMID: 29191893
No abstract available.
8.
Bakst R, Xiong H, Chen C, Deborde S, Lyubchik A, Zhou Y, et al.
Cancer Res
. 2017 Sep;
77(22):6400-6414.
PMID: 28951461
Perineural invasion (PNI) is an ominous event strongly linked to poor clinical outcome. Cells residing within peripheral nerves collaborate with cancer cells to enable PNI, but the contributing conditions within...
9.
Quail D, Olson O, Bhardwaj P, Walsh L, Akkari L, Quick M, et al.
Nat Cell Biol
. 2017 Jul;
19(8):974-987.
PMID: 28737771
Obesity is associated with chronic, low-grade inflammation, which can disrupt homeostasis within tissue microenvironments. Given the correlation between obesity and relative risk of death from cancer, we investigated whether obesity-associated...
10.
Olson O, Kim H, Quail D, Foley E, Joyce J
Cell Rep
. 2017 Apr;
19(1):101-113.
PMID: 28380350
Antimitotic agents, including Taxol, disrupt microtubule dynamics and cause a protracted mitotic arrest and subsequent cell death. Despite the broad utility of these drugs in breast cancer and other tumor...