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Si Yi Zhang

Explore the profile of Si Yi Zhang including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 201
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Recent Articles
1.
Kang Y, Paik H, Zhang S, Chen J, Olson O, Mitchell C, et al.
J Exp Med . 2023 Apr; 220(8). PMID: 37115584
Hematopoietic stem cells (HSC) and downstream lineage-biased multipotent progenitors (MPP) tailor blood production and control myelopoiesis on demand. Recent lineage tracing analyses revealed MPPs to be major functional contributors to...
2.
Mitchell C, Verovskaya E, Calero-Nieto F, Olson O, Swann J, Wang X, et al.
Nat Cell Biol . 2023 Jan; 25(1):30-41. PMID: 36650381
Haematopoietic ageing is marked by a loss of regenerative capacity and skewed differentiation from haematopoietic stem cells (HSCs), leading to impaired blood production. Signals from the bone marrow niche tailor...
3.
Ho T, Dellorusso P, Verovskaya E, Bakker S, Flach J, Smith L, et al.
J Exp Med . 2021 May; 218(7). PMID: 34032859
While young blood can restore many aged tissues, its effects on the aged blood system itself and old hematopoietic stem cells (HSCs) have not been determined. Here, we used transplantation,...
4.
Herault A, Binnewies M, Leong S, Calero-Nieto F, Zhang S, Kang Y, et al.
Nature . 2017 Mar; 544(7648):53-58. PMID: 28355185
Although many aspects of blood production are well understood, the spatial organization of myeloid differentiation in the bone marrow remains unknown. Here we use imaging to track granulocyte/macrophage progenitor (GMP)...