Nynke Kramer
Overview
Explore the profile of Nynke Kramer including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
109
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0
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Recent Articles
1.
Kienhuis A, Krul C, van Engelen J, Evelo C, Hessel E, Hoekman J, et al.
ALTEX
. 2024 Oct;
42(1):111-120.
PMID: 39396389
The Virtual Human Platform for Safety Assessment (VHP4Safety) project aims to build a virtual human platform (VHP) to protect human health and revolutionize the safety assessment of chemicals and pharmaceuticals...
2.
Callewaert E, Louisse J, Kramer N, Sanz-Serrano J, Vinken M
Methods Mol Biol
. 2024 Sep;
2834:249-273.
PMID: 39312169
Adverse outcome pathways (AOPs) describe toxicological processes from a dynamic perspective by linking a molecular initiating event to a specific adverse outcome via a series of key events and key...
3.
Najjar A, Kramer N, Gardner I, Hartung T, Steger-Hartmann T
Front Pharmacol
. 2023 Aug;
14:1257423.
PMID: 37601064
No abstract available.
4.
Astuto M, Di Nicola M, Tarazona J, Rortais A, Devos Y, Liem A, et al.
Methods Mol Biol
. 2022 Feb;
2425:589-636.
PMID: 35188648
This chapter aims to introduce the reader to the basic principles of environmental risk assessment of chemicals and highlights the usefulness of tiered approaches within weight of evidence approaches in...
5.
Vinken M, Benfenati E, Busquet F, Castell J, Clevert D, de Kok T, et al.
Toxicology
. 2021 Jul;
458:152846.
PMID: 34216698
The 3Rs concept, calling for replacement, reduction and refinement of animal experimentation, is receiving increasing attention around the world, and has found its way to legislation, in particular in the...
6.
Toma C, Manganaro A, Raitano G, Marzo M, Gadaleta D, Baderna D, et al.
Molecules
. 2021 Jan;
26(1).
PMID: 33383938
Carcinogenicity is a crucial endpoint for the safety assessment of chemicals and products. During the last few decades, the development of quantitative structure-activity relationship ((Q)SAR) models has gained importance for...
7.
Carnesecchi E, Toma C, Roncaglioni A, Kramer N, Benfenati E, Dorne J
Sci Total Environ
. 2020 Jun;
735:139243.
PMID: 32480144
Honey bees (Apis mellifera) provide key ecosystem services as pollinators bridging agriculture, the food chain and ecological communities, thereby ensuring food production and security. Ecological risk assessment of single Plant...
8.
Vinken M, Kramer N, Allen T, Hoffmans Y, Thatcher N, Levorato S, et al.
Arch Toxicol
. 2020 Feb;
94(3):959-966.
PMID: 32065296
In the last decade, adverse outcome pathways have been introduced in the fields of toxicology and risk assessment of chemicals as pragmatic tools with broad application potential. While their use...
9.
Carnesecchi E, Toropov A, Toropova A, Kramer N, Svendsen C, Dorne J, et al.
Sci Total Environ
. 2019 Dec;
704:135302.
PMID: 31810690
Pollinators such as honey bees are of considerable importance, because of the crucial pollination services they provide for food crops and wild plants. Since bees are exposed to a wide...
10.
Carnesecchi E, Svendsen C, Lasagni S, Grech A, Quignot N, Amzal B, et al.
Environ Int
. 2019 Nov;
133(Pt B):105256.
PMID: 31683157
Bees are exposed to a wide range of multiple chemicals "chemical mixtures" from anthropogenic (e.g. plant protection products or veterinary products) or natural origin (e.g. mycotoxins, plant toxins). Quantifying the...