Aldert H Piersma
Overview
Explore the profile of Aldert H Piersma including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
160
Citations
2025
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dierichs N, Piersma A, Peeters R, Visser W, Meima M, Hessel E
Crit Rev Toxicol
. 2025 Mar;
:1-17.
PMID: 40062460
Thyroid hormone (TH) is crucial for proper neurodevelopment. Insufficient TH concentrations in early life are associated with lower IQ and delayed motor development in children. Intracellular levels of TH are...
2.
Berkhout J, Glazier J, Piersma A, Belmonte J, Legler J, Spencer R, et al.
Curr Res Toxicol
. 2025 Mar;
8:100210.
PMID: 40034255
Neural tube closure is a critical morphogenetic event during early vertebrate development. This complex process is susceptible to perturbation by genetic errors and chemical disruption, which can induce severe neural...
3.
Kienhuis A, Krul C, van Engelen J, Evelo C, Hessel E, Hoekman J, et al.
ALTEX
. 2024 Oct;
42(1):111-120.
PMID: 39396389
The Virtual Human Platform for Safety Assessment (VHP4Safety) project aims to build a virtual human platform (VHP) to protect human health and revolutionize the safety assessment of chemicals and pharmaceuticals...
4.
Roos P, Anggasta C, Piersma A, van Meer P, Theunissen P
Crit Rev Toxicol
. 2024 Aug;
54(9):619-633.
PMID: 39093553
Embryofetal development (EFD) studies are performed to characterize risk of drugs in pregnant women and on embryofetal development. In line with the ICH S5(R3) guideline, these studies are generally conducted...
5.
Homberg J, Piersma A, Krul C, Genzel L, Kienhuis A, Ter Gast E, et al.
Front Vet Sci
. 2024 Jun;
11:1303744.
PMID: 38863453
There is a long-standing debate about experimental non-human animals and animal-free methods in scientific research. Among the various stakeholders involved in the debate are the scientists. During media broadcasts we,...
6.
Meerman J, Legler J, Piersma A, Westerink R, Heusinkveld H
Neurotoxicology
. 2023 Nov;
99:226-243.
PMID: 37926220
Exposure to pesticides is associated with an increased risk of developing Parkinson's disease (PD). Currently, rodent-based risk assessment studies cannot adequately capture neurodegenerative effects of pesticides due to a lack...
7.
Samrani L, Dumont F, Hallmark N, Bars R, Tinwell H, Pallardy M, et al.
Toxicol Lett
. 2023 Jul;
384:96-104.
PMID: 37451652
The evaluation of chemical and pharmaceutical safety for humans is moving from animal studies to New Approach Methodologies (NAM), reducing animal use and focusing on mechanism of action, whilst enhancing...
8.
Samrani L, Dumont F, Hallmark N, Bars R, Tinwell H, Pallardy M, et al.
Reprod Toxicol
. 2023 May;
119:108404.
PMID: 37207909
The zebrafish embryo (ZE) model provides a developmental model well conserved throughout vertebrate embryogenesis, with relevance for early human embryo development. It was employed to search for gene expression biomarkers...
9.
Corradi M, de Haan A, Staumont B, Piersma A, Geris L, Pieters R, et al.
Biomater Biosyst
. 2023 Feb;
7:100061.
PMID: 36824484
Adverse Outcome Pathways (AOPs) are conceptual frameworks that tie an initial perturbation (molecular initiating event) to a phenotypic toxicological manifestation (adverse outcome), through a series of steps (key events). They...
10.
Fragki S, Louisse J, Bokkers B, Luijten M, Peijnenburg A, Rijkers D, et al.
Food Chem Toxicol
. 2022 Dec;
172:113559.
PMID: 36535450
PER: and polyfluoroalkyl substances (PFASs) have been associated with increased blood lipids in humans. Perfluorooctanoic acid (PFOA) has been also linked with elevated alanine transferase (ALT) serum levels in humans,...