Nimrat Chatterjee
Overview
Explore the profile of Nimrat Chatterjee including associated specialties, affiliations and a list of published articles.
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21
Citations
1046
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Recent Articles
1.
DeCleene N, Asik E, Sanchez A, Williams C, Kabotyanski E, Zhao N, et al.
bioRxiv
. 2024 Oct;
PMID: 39416207
Diamond Blackfan anemia (DBA) is caused by germline heterozygous loss-of-function pathogenic variants (PVs) in ribosomal protein (RP) genes, most commonly and . In addition to red cell aplasia, individuals with...
2.
Zaino A, Dash R, James S, MacGilvary N, Crompton A, McPherson K, et al.
Bioorg Med Chem
. 2024 May;
106:117755.
PMID: 38749343
Translesion synthesis (TLS) is a cellular mechanism through which actively replicating cells recruit specialized, low-fidelity DNA polymerases to damaged DNA to allow for replication past these lesions. REV1 is one...
3.
McPherson K, Rizzo A, Erlandsen H, Chatterjee N, Walker G, Korzhnev D
J Biol Chem
. 2023 Jan;
299(2):102859.
PMID: 36592930
Translesion synthesis (TLS) DNA polymerase Polζ is crucial for the bypass replication over sites of DNA damage. The Rev7 subunit of Polζ is a HORMA (Hop1, Rev7, Mad2) protein that...
4.
Bouffard N, Lee K, DeLance N, Clason T, Chatterjee N, Taatjes D
Histochem Cell Biol
. 2022 Oct;
159(2):119-125.
PMID: 36260111
Quantitative analysis of microscopy images from samples stained with fluorescent probes necessitates a very low fluorescence background signal. In tissues prepared by immersion in a chemical fixative, followed by conventional...
5.
Victor J, Jordan T, Lamkin E, Ikeh K, March A, Frere J, et al.
Res Sq
. 2022 Apr;
PMID: 35441168
The repertoire of coronavirus disease 2019 (COVID-19)-mediated adverse health outcomes has continued to expand in infected patients, including the susceptibility to developing long-COVID; however, the molecular underpinnings at the cellular...
6.
Ikeh K, Lamkin E, Crompton A, Deutsch J, Fisher K, Gray M, et al.
Cancers (Basel)
. 2021 Nov;
13(21).
PMID: 34771454
Cancer therapy resistance is a persistent clinical challenge. Recently, inhibition of the mutagenic translesion synthesis (TLS) protein REV1 was shown to enhance tumor cell response to chemotherapy by triggering senescence...
7.
Victor J, Deutsch J, Whitaker A, Lamkin E, March A, Zhou P, et al.
Biochem Biophys Res Commun
. 2021 Oct;
579:141-145.
PMID: 34600299
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus responsible for the current COVID-19 pandemic and has now infected more than 200 million people with more than 4 million...
8.
Chatterjee N, Whitman M, Harris C, Min S, Jonas O, Lien E, et al.
Proc Natl Acad Sci U S A
. 2020 Nov;
117(46):28918-28921.
PMID: 33168727
REV1/POLζ-dependent mutagenic translesion synthesis (TLS) promotes cell survival after DNA damage but is responsible for most of the resulting mutations. A novel inhibitor of this pathway, JH-RE-06, promotes cisplatin efficacy...
9.
Chatterjee N, DSouza S, Shabab M, Harris C, Hilinski G, Verdine G, et al.
Environ Mol Mutagen
. 2020 Jun;
61(8):830-836.
PMID: 32573829
Stapled α-helical RIR (Rev1-interacting region) peptides of DNA POL κ bind more effectively to the RIR-interface of the C-terminal recruitment domain of the translesion synthesis DNA polymerase Rev1 than unstapled...
10.
Dash R, Ozen Z, McCarthy K, Chatterjee N, Harris C, Rizzo A, et al.
ChemMedChem
. 2019 Jul;
14(17):1610-1617.
PMID: 31361935
Translesion synthesis (TLS) has emerged as a mechanism through which several forms of cancer develop acquired resistance to first-line genotoxic chemotherapies by allowing replication to continue in the presence of...