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Nicole Motl

Explore the profile of Nicole Motl including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 283
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Recent Articles
1.
Kabil O, Motl N, Strack M, Seravalli J, Metzler-Nolte N, Banerjee R
J Biol Chem . 2018 Jul; 293(32):12429-12439. PMID: 29980601
Hydrogen sulfide (HS) is a signaling molecule with many beneficial effects. However, its cellular concentration is strictly regulated to avoid toxicity. Persulfide dioxygenase (PDO or ETHE1) is a mononuclear non-heme...
2.
Libiad M, Motl N, Akey D, Sakamoto N, Fearon E, Smith J, et al.
J Biol Chem . 2018 Jan; 293(8):2675-2686. PMID: 29348167
Rhodanese domains are structural modules present in the sulfurtransferase superfamily. These domains can exist as single units, in tandem repeats, or fused to domains with other activities. Despite their prevalence...
3.
Motl N, Skiba M, Kabil O, Smith J, Banerjee R
J Biol Chem . 2017 Jul; 292(34):14026-14038. PMID: 28684420
Hydrogen sulfide (HS) is a signaling molecule that is toxic at elevated concentrations. In eukaryotes, it is cleared via a mitochondrial sulfide oxidation pathway, which comprises sulfide quinone oxidoreductase, persulfide...
4.
Banerjee R, Chiku T, Kabil O, Libiad M, Motl N, Yadav P
Methods Enzymol . 2015 Mar; 554:189-200. PMID: 25725523
H2S is produced from sulfur-containing amino acids, cysteine and homocysteine, or a catabolite, 3-mercaptopyruvate, by three known enzymes: cystathionine β-synthase, γ-cystathionase, and 3-mercaptopyruvate sulfurtransferase. Of these, the first two enzymes...
5.
Kabil O, Motl N, Banerjee R
Biochim Biophys Acta . 2014 Jan; 1844(8):1355-66. PMID: 24418393
Hydrogen sulfide (H2S) has emerged as an important gaseous signaling molecule that is produced endogenously by enzymes in the sulfur metabolic network. H2S exerts its effects on multiple physiological processes...
6.
Kramer R, Shende V, Motl N, Pace C, Scholtz J
Biophys J . 2012 Jul; 102(8):1907-15. PMID: 22768947
Protein solubility is a problem for many protein chemists, including structural biologists and developers of protein pharmaceuticals. Knowledge about how intrinsic factors influence solubility is limited due to the difficulty...
7.
Wei C, Motl N, Levek K, Chen L, Yang Y, Johnson T, et al.
Open Biochem J . 2010 Jul; 4:59-67. PMID: 20648216
Superoxide generated by human NADPH oxidase 5 (NOX5) is of growing importance for various physiological and pathological processes. The activity of NOX5 appears to be regulated by a self-contained Ca(2+)...