Liu Qi Chen
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Explore the profile of Liu Qi Chen including associated specialties, affiliations and a list of published articles.
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10
Citations
398
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Recent Articles
1.
Heitz B, Branstrom R, Yang W, Huang Y, Moede T, Leibiger I, et al.
Sci Rep
. 2021 Nov;
11(1):21539.
PMID: 34728728
ATP-sensitive K (K) channels couple cellular metabolism to electrical activity in many cell types. Wild-type K channels are comprised of four pore forming (Kir6.x) and four regulatory (sulfonylurea receptor, SURx)...
2.
Moon B, Jones K, Chen L, Liu P, Randtke E, Howison C, et al.
Contrast Media Mol Imaging
. 2015 Jun;
10(6):446-55.
PMID: 26108564
Acidosis within tumor and kidney tissues has previously been quantitatively measured using a molecular imaging technique known as acidoCEST MRI. The previous studies used iopromide and iopamidol, two iodinated contrast...
3.
Chen L, Randtke E, Jones K, Moon B, Howison C, Pagel M
Mol Imaging Biol
. 2015 Jan;
17(4):488-96.
PMID: 25622809
Purpose: We aimed to develop pixelwise maps of tumor acidosis to aid in evaluating extracellular tumor pH (pHe) in cancer biology. Procedures: MCF-7 and MDA-MB-231 mouse models were imaged during...
4.
Chen L, Pagel M
Adv Radiol
. 2015 Jan;
2015.
PMID: 27761517
Tumor acidosis is a consequence of altered metabolism, which can lead to chemoresistance and can be a target of alkalinizing therapies. Noninvasive measurements of the extracellular pH (pHe) of the...
5.
Chen L, Howison C, Spier C, Stopeck A, Malm S, Pagel M, et al.
Leuk Lymphoma
. 2014 Aug;
56(5):1432-9.
PMID: 25130478
The expression of carbonic anhydrase IX (CA IX) and its relationship to acidosis in lymphomas has not been widely studied. We investigated the protein expression of CA IX in a...
6.
Randtke E, Chen L, Pagel M
Contrast Media Mol Imaging
. 2014 Apr;
9(3):252-8.
PMID: 24700753
Magnetic resonance imaging (MRI) contrast media that are detected via chemical exchange saturation transfer (CEST) often require an accurate estimation of their chemical exchange rate, kex . A variety of...
7.
Chen L, Howison C, Jeffery J, Robey I, Kuo P, Pagel M
Magn Reson Med
. 2013 Nov;
72(5):1408-17.
PMID: 24281951
Purpose: A practical, noninvasive method is needed to measure the extracellular pH (pHe) within in vivo tumors to longitudinally monitor tumor acidosis. We have optimized a biomedical imaging method, termed...
8.
Randtke E, Chen L, Corrales L, Pagel M
Magn Reson Med
. 2013 Jun;
71(4):1603-12.
PMID: 23780911
Purpose: Contrast agents for chemical exchange saturation transfer MRI often require an accurate measurement of the chemical exchange rate. Many analysis methods have been reported that measure chemical exchange rates....
9.
Sheth V, Li Y, Chen L, Howison C, Flask C, Pagel M
Magn Reson Med
. 2011 Oct;
67(3):760-8.
PMID: 22028287
Paramagnetic chemical exchange saturation transfer (PARACEST) MRI contrast agents have been developed that can measure pH in solution studies, but these agents have not previously been detected in vivo. To...
10.
Wei C, Motl N, Levek K, Chen L, Yang Y, Johnson T, et al.
Open Biochem J
. 2010 Jul;
4:59-67.
PMID: 20648216
Superoxide generated by human NADPH oxidase 5 (NOX5) is of growing importance for various physiological and pathological processes. The activity of NOX5 appears to be regulated by a self-contained Ca(2+)...