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Ruma Banerjee

Explore the profile of Ruma Banerjee including associated specialties, affiliations and a list of published articles. Areas
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Articles 250
Citations 8443
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Recent Articles
1.
Xu Y, Banerjee R, Kasibhatla S, Joshi R, Borah Slater K
J Biol Chem . 2025 Feb; :108288. PMID: 39929299
Mycobacterium tuberculosis (Mtb) is one of the world's successful pathogens that flexibly adapts its metabolic nature during infection of the host, and in response to drugs. Here we used genome...
2.
Yan G, Pan M, Keller A, Santiago A, Lofgren M, Banerjee R, et al.
bioRxiv . 2025 Jan; PMID: 39829891
Significance Statement: MMAB is important for B -dependent propionate metabolism in bacteria. Our findings reveal that conformation-driven binding mechanism underlines the negative cooperativity of MMAB, as it favors the binding...
3.
Hanna D, Chen B, Shah Y, Khalimonchuk O, Cunniff B, Banerjee R
bioRxiv . 2024 Nov; PMID: 39553932
Significance Statement: Hydrogen sulfide is a product of host as well as gut microbial metabolism and has the dual capacity for activating respiration as a substrate, and inhibiting it at...
4.
Gouda H, Ji Y, Rath S, Watkins D, Rosenblatt D, Mootha V, et al.
J Biol Chem . 2024 Aug; 300(9):107662. PMID: 39128713
Propionic acid links the oxidation of branched-chain amino acids and odd-chain fatty acids to the TCA cycle. Gut microbes ferment complex fiber remnants, generating high concentrations of short chain fatty...
5.
Bharti N, Banerjee R, Achalare A, Kasibhatla S, Joshi R
BMC Genom Data . 2024 Jul; 25(1):72. PMID: 39060965
Background: Vitiligo is an auto-immune progressive depigmentation disorder of the skin due to loss of melanocytes. Genetic risk is one of the important factors for development of vitiligo. Preponderance of...
6.
Ruetz M, Mascarenhas R, Widner F, Kieninger C, Koutmos M, Krautler B, et al.
Biochemistry . 2024 Jul; 63(15):1955-1962. PMID: 39012171
In mammals, cobalamin is an essential cofactor that is delivered by a multitude of chaperones in an elaborate trafficking pathway to two client enzymes, methionine synthase and methylmalonyl-CoA mutase (MMUT)....
7.
Vitvitsky V, Kumar R, Diessl J, Hanna D, Banerjee R
J Biol Chem . 2024 Apr; 300(5):107301. PMID: 38641068
Ubiquinol or coenzyme Q (CoQ) is a lipid-soluble electron carrier in the respiratory chain and an electron acceptor for various enzymes in metabolic pathways that intersect at this cofactor hub...
8.
Banerjee R, Block K
Trends Biochem Sci . 2024 Mar; 49(6):471-474. PMID: 38514275
Discoveries at the frontiers of science and finding solutions to pressing biomedical problems will be accelerated when talent, which is widely distributed, is better aligned with opportunities. Strategies to enhance...
9.
Kumar R, Vitvitsky V, Sethaudom A, Singhal R, Solanki S, Alibeckoff S, et al.
Nat Chem Biol . 2024 Mar; 20(10):1294-1304. PMID: 38509349
Angiogenic programming in the vascular endothelium is a tightly regulated process for maintaining tissue homeostasis and is activated in tissue injury and the tumor microenvironment. The metabolic basis of how...
10.
Benchoam D, Cuevasanta E, Roman J, Banerjee R, Alvarez B
J Biol Chem . 2024 Mar; 300(5):107149. PMID: 38479599
Persulfides (RSSH/RSS) participate in sulfur metabolism and are proposed to transduce hydrogen sulfide (HS) signaling. Their biochemical properties are poorly understood. Herein, we studied the acidity and nucleophilicity of several...