Nicolas Sluis-Cremer
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Explore the profile of Nicolas Sluis-Cremer including associated specialties, affiliations and a list of published articles.
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104
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1718
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Recent Articles
11.
Magnus M, Segarra L, Robinson B, Blankenship K, Corneli A, Ghebremichael M, et al.
J Acquir Immune Defic Syndr
. 2023 Sep;
94(2S):S13-S20.
PMID: 37707843
Background: The Centers for AIDS Research Diversity, Equity, and Inclusion Pathway Initiative (CDEIPI) aims to establish programs to develop pathways for successful careers in HIV science among scholars from underrepresented...
12.
Greenberg A, Bowleg L, Robinson B, Magnus M, Segarra L, Simon P, et al.
J Acquir Immune Defic Syndr
. 2023 Sep;
94(2S):S5-S12.
PMID: 37707842
Background: There is an urgent need to increase diversity among scientific investigators in the HIV research field to be more reflective of communities highly affected by the HIV epidemic. Thus,...
13.
14.
Mansouri M, Rumrill S, Dawson S, Johnson A, Pinson J, Gunzburg M, et al.
Molecules
. 2023 Apr;
28(7).
PMID: 37049868
Human immunodeficiency virus type I (HIV-1) is a retrovirus that infects cells of the host's immune system leading to acquired immunodeficiency syndrome and potentially death. Although treatments are available to...
15.
Vargas B, Boslett J, Yates N, Sluis-Cremer N
Biomolecules
. 2023 Jan;
13(1).
PMID: 36671485
The "block and lock" strategy is one approach that might elicit a sterilizing cure for HIV-1 infection. The "block" refers to a compound's ability to inhibit latent HIV-1 proviral transcription,...
16.
El-Khoury C, Mansour E, Yuliandra Y, Lai F, Hawkins B, Du J, et al.
RSC Med Chem
. 2022 Nov;
13(11):1276-1299.
PMID: 36439977
Antibacterial resistance is a prominent issue with monotherapy often leading to treatment failure in serious infections. Many mechanisms can lead to antibacterial resistance including deactivation of antibacterial agents by bacterial...
17.
Xi Z, Ilina T, Guerrero M, Fan L, Sluis-Cremer N, Wang Y, et al.
Protein Sci
. 2022 Apr;
31(5):e4307.
PMID: 35481647
HIV-1 reverse transcriptase (RT) is a heterodimer comprised p66 and p51 subunits (p66/p51). Several single amino acid substitutions in RT, including L289K, decrease p66/p51 dimer affinity, and reduce enzymatic functioning....
18.
Ilina T, Brosenitsch T, Sluis-Cremer N, Ishima R
Enzymes
. 2021 Dec;
50:227-247.
PMID: 34861939
All retroviruses encode the enzyme, reverse transcriptase (RT), which is involved in the conversion of the single-stranded viral RNA genome into double-stranded DNA. RT is a multifunctional enzyme and exhibits...
19.
Sluis-Cremer N
Enzymes
. 2021 Dec;
50:179-194.
PMID: 34861936
Reverse transcriptase (RT) is a multifunctional enzyme that has RNA- and DNA-dependent DNA polymerase activity and ribonuclease H (RNase H) activity, and is responsible for the reverse transcription of retroviral...
20.
Wei Y, Sluis-Cremer N
Antimicrob Agents Chemother
. 2021 Mar;
65(6).
PMID: 33722887
No abstract available.