John W Mellors
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Explore the profile of John W Mellors including associated specialties, affiliations and a list of published articles.
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335
Citations
11853
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Recent Articles
1.
Ehrenberg P, Geretz A, Volcic M, Izumi T, Yum L, Waickman A, et al.
bioRxiv
. 2024 Nov;
PMID: 39605411
Elimination of latent HIV-1 is a major goal of AIDS research but the host factors determining the size of these reservoirs are poorly understood. Here, we investigated whether differences in...
2.
Cyktor J, Yeh E, Ribaudo H, Hoeth D, Naqvi A, Bell T, et al.
J Acquir Immune Defic Syndr
. 2024 Sep;
96(5):481-485.
PMID: 39287554
Background: People with HIV-1 often have chronic inflammation leading to severe non-AIDS morbidity and mortality. The AIDS Clinical Trials Group Study A5314 sought to lower inflammation with low-dose methotrexate (LDMTX)....
3.
Liang T, Sun Z, Hines M, Penrose K, Hao Y, Chu X, et al.
Brief Bioinform
. 2024 Sep;
25(5).
PMID: 39285513
Therapeutic antibody design has garnered widespread attention, highlighting its interdisciplinary importance. Advancements in technology emphasize the critical role of designing nanobodies and humanized antibodies in antibody engineering. However, current experimental...
4.
Paul M, Choudhary M, Heaps A, Deo R, Moisi D, Gordon K, et al.
Pathog Immun
. 2024 Sep;
9(2):79-93.
PMID: 39247686
Background: Anti-SARS-CoV-2 monoclonal antibodies (mAbs) have played a key role as an anti-viral against SARS-CoV-2, but there is a potential for resistance to develop. The interplay between host antibody responses...
5.
Koss C, Gandhi M, Halvas E, Okochi H, Chu C, Glidden D, et al.
Open Forum Infect Dis
. 2024 Sep;
11(9):ofae468.
PMID: 39229286
Background: Long-acting cabotegravir (CAB-LA) is highly effective for HIV prevention, but delayed HIV diagnoses and integrase strand transfer inhibitor (INSTI) resistance were observed in trials. We report the first case...
6.
Morris B, Hixson E, Klamar-Blain C, Gillespie D, Abebe K, Rinaldo C, et al.
J Leukoc Biol
. 2024 Aug;
117(1).
PMID: 39217408
Twelve weeks of dipyridamole increased extracellular adenosine levels and decreased T cell activation in people with human immunodeficiency virus (HIV). In this analysis, we investigated the effect of dipyridamole on...
7.
Capoferri A, Wiegand A, Hong F, Jacobs J, Spindler J, Musick A, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(36):e2405210121.
PMID: 39190360
In the absence of antiretroviral therapy (ART), a subset of individuals, termed HIV controllers, have levels of plasma viremia that are orders of magnitude lower than non-controllers (NC) who are...
8.
Parikh U, Heaps A, Moisi D, Gordon K, Mellors J, Choudhary M, et al.
Pathog Immun
. 2024 Aug;
9(2):58-78.
PMID: 39165724
Background: Assessing the breadth and duration of antigen-specific binding antibodies provides valuable information for evaluating interventions to treat or prevent SARS-CoV-2 infection. Multiplex immunoassays are a convenient method for rapid...
9.
Chu X, Shin S, Baek D, Zhang L, Conard A, Shi M, et al.
MAbs
. 2024 Aug;
16(1):2387240.
PMID: 39113562
Prostate stem cell antigen (PSCA) is expressed in all stages of prostate cancer, including in advanced androgen-independent tumors and bone metastasis. PSCA may associate with prostate carcinogenesis and lineage plasticity...
10.
Landovitz R, Delany-Moretlwe S, Fogel J, Marzinke M, Piwowar-Manning E, Richardson P, et al.
N Engl J Med
. 2024 Jul;
391(13):1253-1256.
PMID: 39046350
No abstract available.