Nicolas Demaurex
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Explore the profile of Nicolas Demaurex including associated specialties, affiliations and a list of published articles.
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105
Citations
4033
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Recent Articles
21.
Sedlyarov V, Eichner R, Girardi E, Essletzbichler P, Goldmann U, Nunes-Hasler P, et al.
Cell Host Microbe
. 2018 May;
23(6):766-774.e5.
PMID: 29779931
Macrophages represent the first line of immune defense against pathogens, and phagosome acidification is a necessary step in pathogen clearance. Here, we identified the bicarbonate transporter SLC4A7, which is strongly...
22.
Nunes P, Demaurex N
Cell Calcium
. 2018 Apr;
73:70-71.
PMID: 29684786
GRAM domain proteins were reported as novel ER-PM tethers defining specific membrane contact sites (MCS) subdomains. GRAMD2a pre-marks the sites occupied by STIM1 at MCS and its ablation impairs STIM1...
23.
Demaurex N, Saul S
J Physiol
. 2018 Feb;
596(14):2699-2708.
PMID: 29441588
Stromal interaction molecule (STIM) proteins regulate store-operated Ca entry (SOCE) in innate and adaptive immune cells and participate in the Ca signals that control the functions of neutrophils, the first...
24.
Nunes-Hasler P, Maschalidi S, Lippens C, Castelbou C, Bouvet S, Guido D, et al.
Nat Commun
. 2017 Nov;
8(1):1852.
PMID: 29176619
Antigen cross-presentation by dendritic cells (DC) stimulates cytotoxic T cell activation to promote immunity to intracellular pathogens, viruses and cancer. Phagocytosed antigens generate potent T cell responses, but the signalling...
25.
Maschalidi S, Nunes-Hasler P, Nascimento C, Sallent I, Lannoy V, Garfa-Traore M, et al.
Nat Commun
. 2017 Nov;
8(1):1640.
PMID: 29158474
Dendritic cells (DC) have the unique ability to present exogenous antigens via the major histocompatibility complex class I pathway to stimulate naive CD8 T cells. In DCs with a non-functional...
26.
Demaurex N, Guido D
Adv Exp Med Biol
. 2017 Sep;
993:277-296.
PMID: 28900920
Store-operated Ca entry (SOCE) is a cell signaling pathway essential for immune and muscle function controlled by dynamic interactions between Ca-sensing STIM proteins on the endoplasmic reticulum (ER) and Ca-permeable...
27.
Vernay A, Marchetti A, Sabra A, Jauslin T, Rosselin M, Scherer P, et al.
Proc Natl Acad Sci U S A
. 2017 Jul;
114(31):8277-8282.
PMID: 28716905
MitoNEET (mNEET) is a dimeric mitochondrial outer membrane protein implicated in many facets of human pathophysiology, notably diabetes and cancer, but its molecular function remains poorly characterized. In this study,...
28.
Wiederkehr A, Demaurex N
Nat Methods
. 2017 Jun;
14(7):671-672.
PMID: 28661497
No abstract available.
29.
Nunes-Hasler P, Demaurex N
Biochim Biophys Acta Mol Cell Res
. 2017 Apr;
1864(9):1513-1524.
PMID: 28432021
Phagocytosis is an essential mechanism through which innate immune cells ingest foreign material that is either destroyed or used to generate and present antigens and initiate adaptive immune responses. While...
30.
Demaurex N, Rosselin M
Mol Cell
. 2017 Mar;
65(6):961-962.
PMID: 28306510
Dong et al. (2017) establish how the mitochondrial Ca uniporter (MCU) integrates Ca and oxidative stress signals by identifying a cysteine residue that controls MCU channel activity, a mechanism causing...