Nicholas T Woods
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Explore the profile of Nicholas T Woods including associated specialties, affiliations and a list of published articles.
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41
Citations
556
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Recent Articles
11.
Lagundzin D, Krieger K, Law H, Woods N
STAR Protoc
. 2022 Mar;
3(1):101234.
PMID: 35300004
This protocol represents an optimized proteomics-based protocol for the endogenous protein enrichment and protein-protein interaction analysis. This 2-step protocol consists of: 1) co-immunoprecipitation of the bait protein; 2) the bait-protein...
12.
Kour S, Rana S, Kizhake S, Lagundzin D, Klinkebiel D, Mallareddy J, et al.
RSC Chem Biol
. 2022 Feb;
3(1):32-36.
PMID: 35128406
Tumor necrosis factor (TNF) α-induced nuclear translocation of the NF-κB subunit RELA has been implicated in several pathological conditions. Here we report the discovery of a spirocyclic dimer (SpiD7) that...
13.
Mendoza-Fandino G, Lyra Jr P, Nepomuceno T, Harro C, Woods N, Li X, et al.
Eur J Hum Genet
. 2021 Nov;
30(4):465-473.
PMID: 34803163
Genome wide-association studies (GWAS) have established over 400 breast cancer risk loci defined by common single nucleotide polymorphisms (SNPs), including several associated with estrogen-receptor (ER)-negative disease. Most of these loci...
14.
Law H, Clement E, Grandgenett P, Hollingsworth M, Woods N
Clin Cancer Res
. 2021 Jul;
27(14):4127.
PMID: 34261772
No abstract available.
15.
King H, Rana S, Kubica S, Mallareddy J, Kizhake S, Ezell E, et al.
Bioorg Med Chem Lett
. 2021 Apr;
43:128061.
PMID: 33895280
Cyclin-dependent kinase 9 (CDK9) is a member of the cyclin-dependent kinase (CDK) family which is involved in transcriptional regulation of several genes, including the oncogene Myc, and is a validated...
16.
Casey C, Donohue Jr T, Kubik J, Kumar V, Naldrett M, Woods N, et al.
J Lipid Res
. 2021 Feb;
62:100049.
PMID: 33617872
Lipid droplets (LDs) are composed of neutral lipids enclosed in a phospholipid monolayer, which harbors membrane-associated proteins that regulate LD functions. Despite the crucial role of LDs in lipid metabolism,...
17.
Qiao F, Law H, Krieger K, Clement E, Xiao Y, Buckley S, et al.
Biol Open
. 2021 Jan;
10(1).
PMID: 33408128
RNA polymerase II subunit A Carboxy-Terminal Domain Phosphatase 1 (CTDP1), a member of the haloacid dehalogenase superfamily phosphatases, has a defined role in transcriptional regulation, but emerging evidence suggests an...
18.
Swenson S, Gilbreath T, Vahle H, Willow Hynes-Smith R, Graham J, Law H, et al.
Blood
. 2020 Apr;
136(3):299-312.
PMID: 32325489
Coordination of a number of molecular mechanisms including transcription, alternative splicing, and class switch recombination are required to facilitate development, activation, and survival of B cells. Disruption of these pathways...
19.
Law H, Lagundzin D, Clement E, Qiao F, Wagner Z, Krieger K, et al.
Clin Cancer Res
. 2019 Dec;
26(5):1065-1076.
PMID: 31848187
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease that can be separated into distinct subtypes based on molecular signatures. Identifying PDAC subtype-specific therapeutic vulnerabilities is necessary to develop...
20.
Krieger K, Hu W, Ripperger T, Woods N
Int J Mol Sci
. 2019 Nov;
20(23).
PMID: 31771139
Deleterious mutations in Breast Cancer 1 () are associated with an increased risk of breast and ovarian cancer. Mutations in the tandem BRCA1 C-terminal (tBRCT) protein domain disrupt critical protein...