Nicholas L Smith
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Explore the profile of Nicholas L Smith including associated specialties, affiliations and a list of published articles.
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267
Citations
14902
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Recent Articles
1.
Huang Y, Kwan M, Heckbert S, Smith N, Othus M, Laurent C, et al.
J Natl Cancer Inst
. 2025 Mar;
PMID: 40071691
Background: There are increasing concerns of cardiovascular safety related to endocrine therapy use in women with breast cancer (BC). We examined risk of cardiovascular disease (CVD) events and mortality associated...
2.
Choi S, Jurgens S, Xiao L, Hill M, Haggerty C, Sveinbjornsson G, et al.
Nat Genet
. 2025 Mar;
57(3):548-562.
PMID: 40050430
Atrial fibrillation (AF) is a prevalent and morbid abnormality of the heart rhythm with a strong genetic component. Here, we meta-analyzed genome and exome sequencing data from 36 studies that...
3.
Roselli C, Surakka I, S Olesen M, Sveinbjornsson G, Marston N, Choi S, et al.
Nat Genet
. 2025 Mar;
57(3):539-547.
PMID: 40050429
Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart failure and stroke. This large-scale meta-analysis of genome-wide association studies increased the power...
4.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
5.
Huang Y, Kwan M, Heckbert S, Smith N, Othus M, Laurent C, et al.
JNCI Cancer Spectr
. 2025 Jan;
9(1).
PMID: 39873699
Background: There are limited data on duration of aromatase inhibitor (AI) and cardiovascular disease (CVD) risk in breast cancer (BC) survivors. We examined the risk of CVD and mortality associated...
6.
Tokareva K, Peterson A, Baraff A, Chung S, Barton J, Baker J, et al.
BMC Rheumatol
. 2025 Jan;
9(1):7.
PMID: 39819734
Background: Biologic (b) and targeted synthetic (ts) disease-modifying anti-rheumatic drugs (DMARDs) used in the management of rheumatoid arthritis (RA) target inflammatory pathways implicated in the pathogenesis of multiple myeloma (MM)....
7.
Huang Y, Kurniansyah N, Goodman M, Spitzer B, Wang J, Stilp A, et al.
medRxiv
. 2025 Jan;
PMID: 39763564
Polygenic risk scores (PRSs) depend on genetic ancestry due to differences in allele frequencies between ancestral populations. This leads to implementation challenges in diverse populations. We propose a framework to...
8.
Munsch G, Thibord F, Bezerra O, Brody J, van Hylckama Vlieg A, Gourhant L, et al.
medRxiv
. 2024 Dec;
PMID: 39677447
Venous thromboembolism (VT) is a frequent (annual incidence of 1 to 2 per 1,000) and potentially life-threatening (case-fatality rate up to 10%) disease. VT is associated with serious short-term and...
9.
Maccarone J, Redlich C, Timmons A, Korpak A, Smith N, Nakayama K, et al.
J Allergy Clin Immunol Glob
. 2024 Dec;
4(1):100367.
PMID: 39659739
Background: Post-9/11 veterans were exposed to environmental and occupational pollutants during deployment. Objective: Our aim was to determine associations between deployment-related exposures and sinusitis and rhinitis. Methods: Between April 2018...
10.
Burggraaf-van Delft J, Wiggins K, van Rein N, le Cessie S, Smith N, Cannegieter S
Res Pract Thromb Haemost
. 2024 Dec;
8(8):102610.
PMID: 39640909
Background: Long-term outcome after a first venous thromboembolism (VTE) might be optimized by tailoring anticoagulant treatment duration on individual risks of recurrence and major bleeding. The L-TRRiP models (A-D) were...