Alanna C Morrison
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Explore the profile of Alanna C Morrison including associated specialties, affiliations and a list of published articles.
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288
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15418
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Recent Articles
1.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
2.
Lee S, Miller C, Bentley A, Brown M, Nagarajan P, Noordam R, et al.
Res Sq
. 2025 Mar;
PMID: 40034430
Background Gene-environment interactions may enhance our understanding of hypertension. Our previous study highlighted the importance of considering psychosocial factors in gene discovery for blood pressure (BP) but was limited in...
3.
Iyer K, Clarke S, Guarischi-Sousa R, Gjoni K, Heath A, Young E, et al.
J Am Heart Assoc
. 2025 Feb;
14(4):e036499.
PMID: 39950338
Background: Genome-wide association studies have identified several hundred susceptibility single nucleotide variants for coronary artery disease (CAD). Despite single nucleotide variant-based genome-wide association studies improving our understanding of the genetics...
4.
Zhang X, Rahbar M, Tahanan A, Bauer C, de Oliveira Otto M, Morrison A, et al.
Contemp Clin Trials Commun
. 2025 Feb;
44:101438.
PMID: 39935750
Background: Our institution carried out a multi-center, group-randomized controlled trial to evaluate the effectiveness of two community-based interventions on promoting the uptake of COVID-19 testing and vaccination in three regions...
5.
Zhang K, Hunyadi J, de Oliveira Otto M, Lee M, Zhang Z, Ramphul R, et al.
JMIR Form Res
. 2025 Feb;
9:e62802.
PMID: 39935005
Background: Geospatial data science can be a powerful tool to aid the design, reach, efficiency, and impact of community-based intervention trials. The project titled Take Care Texas aims to develop...
6.
Li X, Chen H, Selvaraj M, Van Buren E, Zhou H, Wang Y, et al.
Nat Comput Sci
. 2025 Feb;
5(2):125-143.
PMID: 39920506
Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to complex human traits. Leveraging association effect sizes across multiple traits in...
7.
Huang Y, Kurniansyah N, Goodman M, Spitzer B, Wang J, Stilp A, et al.
medRxiv
. 2025 Jan;
PMID: 39763564
Polygenic risk scores (PRSs) depend on genetic ancestry due to differences in allele frequencies between ancestral populations. This leads to implementation challenges in diverse populations. We propose a framework to...
8.
Li R, Gagliano Taliun S, Liao K, Flickinger M, Sobell J, Genovese G, et al.
medRxiv
. 2025 Jan;
PMID: 39763555
In studies of individuals of primarily European genetic ancestry, common and low-frequency variants and rare coding variants have been found to be associated with the risk of bipolar disorder (BD)...
9.
Harris R, Taylor O, Gramatges M, Hughes A, Zobeck M, Pruitt S, et al.
Pharmacotherapy
. 2024 Dec;
45(1):4-11.
PMID: 39734275
Background: Methotrexate is an important component of curative therapy in childhood acute lymphoblastic leukemia (ALL), but the role of genetic variation influencing methotrexate clearance and transport in toxicity susceptibility in...
10.
Shetty N, Gaonkar M, Pampana A, Patel N, Morrison A, Reiner A, et al.
JACC Heart Fail
. 2024 Nov;
13(1):91-101.
PMID: 39520444
Background: Nearly 3% to 4% of Black individuals in the United States carry the transthyretin V142I variant, which increases their risk of heart failure. However, the role of cardiovascular (CV)...