Andre G Uitterlinden
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Explore the profile of Andre G Uitterlinden including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
2.
Li R, Kurilshikov A, Yang S, van Oortmerssen J, van Hilten A, Ahmadizar F, et al.
Lancet Reg Health Eur
. 2025 Jan;
50():101195.
PMID: 39834614
Background: The human gut microbiome changes considerably over time. Previous studies have shown that gut microbiome profiles correlate with multiple metabolic traits. As disease development is likely a lifelong process,...
3.
Ahmad S, Wu T, Arnold M, Hankemeier T, Ghanbari M, Roshchupkin G, et al.
medRxiv
. 2025 Jan;
PMID: 39763567
Increasing evidence suggests the involvement of metabolic alterations in neurological disorders, including Alzheimer's disease (AD), and highlights the significance of the peripheral metabolome, influenced by genetic factors and modifiable environmental...
4.
Zhou W, van de Laarschot D, van Rooij J, Koedam M, Nguyen H, Uitterlinden A, et al.
J Bone Miner Res
. 2024 Nov;
40(1):69-78.
PMID: 39485938
Atypical femur fractures (AFFs) are rare adverse events associated with bisphosphonate use, having unclear pathophysiology. AFFs also cluster in families and have occurred in patients with monogenetic bone diseases sometimes...
5.
Bertels X, Vauterin D, Riemann S, Van Vaerenbergh F, Proesmans K, Uitterlinden A, et al.
Ann Am Thorac Soc
. 2024 Sep;
PMID: 39311722
Research suggests that respiratory and cardiovascular drugs can ameliorate the rate of lung function decline. To investigate the impact of respiratory and cardiovascular pharmacotherapy on lung function trajectories in the...
6.
van der Perk M, Broer L, Yasui Y, Laven J, Robison L, Tissing W, et al.
Fertil Steril
. 2024 May;
122(3):514-524.
PMID: 38729340
Objective: To discover new variants associated with low ovarian reserve after gonadotoxic treatment among adult female childhood cancer survivors using a genome-wide association study approach. Design: Genome-wide association study. Setting:...
7.
Prijatelj V, Grgic O, Uitterlinden A, Wolvius E, Rivadeneira F, Medina-Gomez C
Bone
. 2024 Mar;
182:117070.
PMID: 38460828
Bone Health Index (BHI) has been proposed as a useful instrument for assessing bone health in children. However, its relationship with fracture risk remains unknown. We aimed to investigate whether...
8.
Sterenborg R, Steinbrenner I, Li Y, Bujnis M, Naito T, Marouli E, et al.
Nat Commun
. 2024 Jan;
15(1):888.
PMID: 38291025
To date only a fraction of the genetic footprint of thyroid function has been clarified. We report a genome-wide association study meta-analysis of thyroid function in up to 271,040 individuals...
9.
de las Fuentes L, Schwander K, Brown M, Bentley A, Winkler T, Sung Y, et al.
Front Genet
. 2023 Nov;
14:1235337.
PMID: 38028628
Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density...
10.
Chen J, Arshi B, Waqas K, Lu T, Bos D, Ikram M, et al.
Cardiovasc Diabetol
. 2023 Nov;
22(1):326.
PMID: 38017418
Background: Advanced glycation end products (AGEs) have been linked to cardiovascular disease (CVD), especially coronary heart disease (CHD), but their role in CVD pathogenesis remains unclear. Therefore, we investigated cross-sectional...