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Kerri L Wiggins

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Articles 105
Citations 6081
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Recent Articles
1.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet . 2025 Mar; PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
2.
Munsch G, Thibord F, Bezerra O, Brody J, van Hylckama Vlieg A, Gourhant L, et al.
medRxiv . 2024 Dec; PMID: 39677447
Venous thromboembolism (VT) is a frequent (annual incidence of 1 to 2 per 1,000) and potentially life-threatening (case-fatality rate up to 10%) disease. VT is associated with serious short-term and...
3.
Burggraaf-van Delft J, Wiggins K, van Rein N, le Cessie S, Smith N, Cannegieter S
Res Pract Thromb Haemost . 2024 Dec; 8(8):102610. PMID: 39640909
Background: Long-term outcome after a first venous thromboembolism (VTE) might be optimized by tailoring anticoagulant treatment duration on individual risks of recurrence and major bleeding. The L-TRRiP models (A-D) were...
4.
Yogeswaran V, Wiggins K, Sitlani C, Ilkhanoff L, Benjamin E, Heckbert S, et al.
JAMA Netw Open . 2024 Oct; 7(10):e2442319. PMID: 39476232
Importance: Resting heart rate (RHR) is a widely available measure of cardiovascular fitness that has been associated with several cardiovascular outcomes. RHR has previously been associated with the risk of...
5.
Mack T, Raddatz M, Pershad Y, Nachun D, Taylor K, Guo X, et al.
Nat Aging . 2024 Jun; 4(8):1043-1052. PMID: 38834882
Clonal hematopoiesis of indeterminate potential (CHIP), whereby somatic mutations in hematopoietic stem cells confer a selective advantage and drive clonal expansion, not only correlates with age but also confers increased...
6.
Hasser E, Brody J, Bartz T, Thibord F, Li-Gao R, Kauko A, et al.
J Thromb Haemost . 2024 May; 22(8):2261-2269. PMID: 38782299
Background: Increased risk of venous thromboembolism (VTE) is a life-threatening side effect for users of oral contraceptives (OCs) or hormone therapy (HT). Objectives: To investigate the potential for genetic predisposition...
7.
Kwak S, Hernandez-Cancela R, DiCorpo D, Condon D, Merino J, Wu P, et al.
Diabetes Care . 2024 Apr; 47(6):1042-1047. PMID: 38652672
Objective: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). Research Design And Methods: We conducted a multiancestry time-to-event genome-wide association study...
8.
Rasouli B, Chubak J, Floyd J, Psaty B, Nguyen M, Walker R, et al.
BMJ . 2023 Dec; 383:e072346. PMID: 38154827
No abstract available.
9.
Zakai N, Wilkinson K, Sparks A, Packer R, Koh I, Roetker N, et al.
J Thromb Haemost . 2023 Nov; 22(2):503-515. PMID: 37918635
Background: Regulatory organizations recommend assessing hospital-acquired (HA) venous thromboembolism (VTE) risk for medical inpatients. Objectives: To develop and validate a risk assessment model (RAM) for HA-VTE in medical inpatients using...
10.
Liu X, Sun X, Zhang Y, Jiang W, Lai M, Wiggins K, et al.
J Am Heart Assoc . 2023 Oct; 12(20):e029090. PMID: 37804200
Background The relationship between mitochondrial DNA copy number (mtDNA CN) and cardiovascular disease remains elusive. Methods and Results We performed cross-sectional and prospective association analyses of blood-derived mtDNA CN and...