Nicholas J Magon
Overview
Explore the profile of Nicholas J Magon including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
196
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Paumann-Page M, Kienzl N, Motwani J, Bathish B, Paton L, Magon N, et al.
Redox Biol
. 2021 Aug;
46:102090.
PMID: 34438259
Peroxidasin, a heme peroxidase, has been shown to play a role in cancer progression. mRNA expression has been reported to be upregulated in metastatic melanoma cell lines and connected to...
12.
Meng Y, Sheen C, Magon N, Hampton M, Dobson R
J Biol Chem
. 2020 Jan;
295(10):2984-2999.
PMID: 31974167
During aerobic growth, the Gram-positive facultative anaerobe and opportunistic human pathogen generates large amounts of hydrogen peroxide that can accumulate to millimolar concentrations. The mechanism by which this catalase-negative bacterium...
13.
Magon N, Parker H, Ashby L, Springer R, Hampton M
Methods Mol Biol
. 2019 Nov;
2087:149-164.
PMID: 31728990
This chapter describes three methods for measuring the bactericidal activity of neutrophils. All utilize colony counting techniques to quantify viable bacteria. A simple "one-step" protocol provides a composite measure of...
14.
Roch A, Magon N, Maire J, Suarna C, Ayer A, Waldvogel S, et al.
JCI Insight
. 2019 Oct;
4(21).
PMID: 31581149
The RBC storage lesion is a multiparametric response that occurs during storage at 4°C, but its impact on transfused patients remains unclear. In studies of the RBC storage lesion, the...
15.
Magon N, Turner R, Gearry R, Hampton M, Sly P, Kettle A
Free Radic Biol Med
. 2015 May;
86:133-44.
PMID: 26006104
Calprotectin provides nutritional immunity by sequestering manganese and zinc ions. It is abundant in the lungs of patients with cystic fibrosis but fails to prevent their recurrent infections. Calprotectin is...
16.
Wilkie-Grantham R, Magon N, Harwood D, Kettle A, Vissers M, Winterbourn C, et al.
J Biol Chem
. 2015 Feb;
290(15):9896-905.
PMID: 25697357
Phagocytic neutrophils generate reactive oxygen species to kill microbes. Oxidant generation occurs within an intracellular phagosome, but diffusible species can react with the neutrophil and surrounding tissue. To investigate the...
17.
Dickerhof N, Magon N, Tyndall J, Kettle A, Hampton M
Biochem J
. 2014 Jun;
462(2):303-14.
PMID: 24916123
MIF (macrophage migration inhibitory factor) plays a central role in the promotion and maintenance of the inflammatory response. It is implicated in a number of inflammatory diseases including sepsis, arthritis...
18.
Parker H, Magon N, Green J, Hampton M, Winterbourn C
Methods Mol Biol
. 2014 Feb;
1124:291-306.
PMID: 24504960
This chapter describes two methods for measuring the bactericidal activity of neutrophils. These are a new simple fluorescence-based assay, which quantifies bactericidal activity by measuring changes in bacterial fluorescence associated...
19.
Tiden A, Sjogren T, Svensson M, Bernlind A, Senthilmohan R, Auchere F, et al.
J Biol Chem
. 2011 Sep;
286(43):37578-89.
PMID: 21880720
Myeloperoxidase (MPO) is a prime candidate for promoting oxidative stress during inflammation. This abundant enzyme of neutrophils uses hydrogen peroxide to oxidize chloride to highly reactive and toxic chlorine bleach....