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Bridget A Robinson

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Articles 72
Citations 1505
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Recent Articles
1.
Song J, Zhang L, Moon S, Fang A, Wang G, Gheshm N, et al.
Sci Adv . 2025 Feb; 11(9):eadu7985. PMID: 40020060
Plasma membrane rupture by Ninjurin-1 (NINJ1) executes programmed cell death, releasing large cellular damage-associated molecular patterns (DAMPs). However, the regulation and selectivity of NINJ1-mediated DAMP release remain unexplored. Here, we...
2.
Burgess E, Praditi C, Phillips E, Vissers M, Robinson B, Dachs G, et al.
J Cell Biochem . 2024 Oct; 126(1):e30658. PMID: 39382087
The most common and aggressive brain cancer, glioblastoma, is characterized by hypoxia and poor survival. The pro-tumour transcription factor, hypoxia-inducible factor (HIF), is regulated via HIF-hydroxylases that require ascorbate as...
3.
Topham B, de Vries M, Nonis M, van Berkel R, Pullar J, Magon N, et al.
Epigenomes . 2024 May; 8(2). PMID: 38804366
The treatment of metastatic melanoma has been revolutionised by immunotherapy, yet a significant number of patients do not respond, and many experience autoimmune adverse events. Associations have been reported between...
4.
de Vries M, Stewart T, Ireton T, Keelan K, Jordan J, Robinson B, et al.
PLoS One . 2023 Aug; 18(8):e0290321. PMID: 37607163
Background: Discrepancies have been reported between what is being researched, and what patients/families deem important to be investigated. Our aim was to understand research priorities for those who live with...
5.
Hakkaart C, Pearson J, Marquart L, Dennis J, Wiggins G, Barnes D, et al.
Commun Biol . 2022 Oct; 5(1):1061. PMID: 36203093
The contribution of germline copy number variants (CNVs) to risk of developing cancer in individuals with pathogenic BRCA1 or BRCA2 variants remains relatively unknown. We conducted the largest genome-wide analysis...
6.
Crake R, Burgess E, Wiggins G, Magon N, Das A, Vissers M, et al.
Sci Rep . 2022 Sep; 12(1):14845. PMID: 36050369
Gliomas are incurable brain cancers with poor prognosis, with epigenetic dysregulation being a distinctive feature. 5-hydroxymethylcytosine (5-hmC), an intermediate generated in the demethylation of 5-methylcytosine, is present at reduced levels...
7.
Leong T, McCook G, Frampton C, Robinson B, James M
J Med Imaging Radiat Oncol . 2022 Jun; 66(7):1003-1013. PMID: 35642730
Introduction: Stage III melanoma is associated with poor outcomes. We studied the characteristics and outcomes of patients with resected Stage III melanoma before the routine use of adjuvant immunotherapy. Some...
8.
Burgess E, Crake R, Phillips E, Morrin H, Royds J, Slatter T, et al.
Front Oncol . 2022 Apr; 12:829524. PMID: 35419292
Glioblastoma multiforme is a challenging disease with limited treatment options and poor survival. Glioblastoma tumours are characterised by hypoxia that activates the hypoxia inducible factor (HIF) pathway and controls a...
9.
Buss L, Hock B, Merry T, Ang A, Robinson B, Currie M, et al.
PLoS One . 2021 Oct; 16(10):e0258831. PMID: 34665826
Cancer causes mitochondrial alterations in skeletal muscle, which may progress to muscle wasting and, ultimately, to cancer cachexia. Understanding how exercise adaptations are altered by cancer and cancer treatment is...
10.
Wohlrab C, Vissers M, Burgess E, Nonis M, Phillips E, Robinson B, et al.
Cell Physiol Biochem . 2021 Oct; 55(5):553-568. PMID: 34599650
Background/aims: Maintenance of whole-body ascorbate levels and distribution is mediated via sodium-dependent vitamin C transporters (SVCTs). The kidney is one of a few organs that express both SVCT1 and SVCT2....