Vanessa K Morris
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Explore the profile of Vanessa K Morris including associated specialties, affiliations and a list of published articles.
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21
Citations
306
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Recent Articles
1.
Heath S, Naughton J, Magon N, Gray S, Smith B, Morris V, et al.
J Biol Chem
. 2024 Jul;
300(8):107590.
PMID: 39032649
The human tumor suppressor p16 is a small monomeric protein that can form amyloid structures. Formation of p16 amyloid fibrils is induced by oxidation which creates an intermolecular disulfide bond....
2.
Heath S, Gray S, Hamzah E, OConnor K, Bozonet S, Botha A, et al.
Nat Commun
. 2024 Jul;
15(1):5535.
PMID: 38951545
The conversion of a soluble protein into polymeric amyloid structures is a process that is poorly understood. Here, we describe a fully redox-regulated amyloid system in which cysteine oxidation of...
3.
Gilkes J, Frampton R, Board A, Hudson A, Price T, Morris V, et al.
Protein Sci
. 2024 Jun;
33(7):e5083.
PMID: 38924211
The effect of population bottlenecks and genome reduction on enzyme function is poorly understood. Candidatus Liberibacter solanacearum is a bacterium with a reduced genome that is transmitted vertically to the...
4.
Bozonet S, Magon N, Schwartfeger A, Konigstorfer A, Heath S, Vissers M, et al.
J Biol Chem
. 2023 May;
299(6):104792.
PMID: 37150321
Necroptosis is a form of regulated cell death triggered by various host and pathogen-derived molecules during infection and inflammation. The essential step leading to necroptosis is phosphorylation of the mixed...
5.
Harper A, Dobson R, Morris V, Moggre G
Microb Biotechnol
. 2022 Apr;
15(5):1404-1421.
PMID: 35393728
Ethical, environmental and health concerns around dairy products are driving a fast-growing industry for plant-based dairy alternatives, but undesirable flavours and textures in available products are limiting their uptake into...
6.
Smyth L, Murray H, Hill M, van Leeuwen E, Highet B, Magon N, et al.
Acta Neuropathol Commun
. 2022 Mar;
10(1):38.
PMID: 35331340
Introduction: Neutrophil accumulation is a well-established feature of Alzheimer's disease (AD) and has been linked to cognitive impairment by modulating disease-relevant neuroinflammatory and vascular pathways. Neutrophils express high levels of...
7.
Ball S, Pham C, Lo V, Morris V, Kwan A, Sunde M
Methods Mol Biol
. 2019 Oct;
2073:55-72.
PMID: 31612436
The fungal hydrophobins are small proteins that are able to self-assemble spontaneously into amphipathic monolayers at hydrophobic:hydrophilic interfaces. These protein monolayers can reverse the wettability of a surface, making them...
8.
Gobl C, Morris V, van Dam L, Visscher M, Polderman P, Hartlmuller C, et al.
Redox Biol
. 2019 Sep;
28:101316.
PMID: 31539802
The tumor suppressor p16 induces cell cycle arrest and senescence in response to oncogenic transformation and is therefore frequently lost in cancer. p16 is also known to accumulate under conditions...
9.
Sun Y, Medina Cruz A, Hadley K, Galant N, Law R, Vernon R, et al.
Biochemistry
. 2018 Nov;
58(6):590-607.
PMID: 30489059
Intraneuronal aggregation of TDP-43 is seen in 97% of all amyotrophic lateral sclerosis cases and occurs by a poorly understood mechanism. We developed a simple in vitro model system for...
10.
Cristovao J, Morris V, Cardoso I, Leal S, Martinez J, Botelho H, et al.
Sci Adv
. 2018 Jul;
4(6):eaaq1702.
PMID: 29963623
Amyloid-β (Aβ) aggregation and neuroinflammation are consistent features in Alzheimer's disease (AD) and strong candidates for the initiation of neurodegeneration. S100B is one of the most abundant proinflammatory proteins that...