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Nicholas A Williamson

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Articles 94
Citations 3870
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Recent Articles
1.
Lin S, Dong L, De Nardo W, Leeming M, Cheng Z, Williamson N, et al.
Am J Physiol Endocrinol Metab . 2025 Feb; 328(3):E377-E394. PMID: 39925140
The prevalence of metabolic dysfunction-associated steatohepatitis (MASH) is increasing at an alarming rate. To date, only one therapy has been provisionally approved for the treatment of MASH and liver fibrosis,...
2.
Murillo E, Martinez-Seidel F, Atanasov K, Gentry-Torfer D, Pereira Firmino A, Erban A, et al.
Plant Physiol Biochem . 2025 Feb; 220:109585. PMID: 39893946
Polyamines are small, polycationic molecules with amino groups that are present in most living organisms. Studies indicate that polyamines increase general protein synthesis and are essential for efficient translation. While...
3.
Wang T, Leeming M, Williamson N, Bouchery T, Doolan R, Le Gros G, et al.
Parasit Vectors . 2025 Jan; 18(1):27. PMID: 39863914
Background: Nippostrongylus brasiliensis-a nematode of rodents-is commonly used as a model to study the immunobiology of parasitic nematodes. It is a member of the Strongylida-a large order of socioeconomically important...
4.
Ivanova E, Nguyen T, Linklater D, Le P, Vilagosh Z, Perera P, et al.
ACS Omega . 2024 Dec; 9(50):49878-49886. PMID: 39713687
The biological effects of electromagnetic field (EMF) irradiation in the terahertz (THz) range remain ambiguous, despite numerous studies that have been conducted. In this paper, the metabolic response of K...
5.
Anari M, Karimkhanloo H, Nie S, Dong L, Fidelito G, Bayliss J, et al.
Cell Rep . 2024 Dec; 43(12):115007. PMID: 39666456
Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by defective lipid metabolism, which causes disease progression. MASH is also linked to various cardiometabolic risk factors, including obesity and type 2 diabetes. The...
6.
Santos Gonzalez F, Hock D, Thorburn D, Mordaunt D, Williamson N, Ang C, et al.
Orphanet J Rare Dis . 2024 Nov; 19(1):443. PMID: 39609890
Background: Mass spectrometry-based quantitative proteomics has a demonstrated utility in increasing the diagnostic yield of mitochondrial disorders (MDs) and other rare diseases. However, for this technology to be widely adopted...
7.
Zhang X, Cheng T, Cho E, Lu W, Denoyer D, McMillan P, et al.
Pharmacol Res . 2024 Nov; 210:107519. PMID: 39603575
Many drugs have been discontinued during phase II/III breast cancer clinical trials due to lack of clinical efficacy, indicating shortcomings in predictive value of preclinical data. Nutrient availability in the...
8.
Zhang S, Owyong T, Sanislav O, Englmaier L, Sui X, Wang G, et al.
Nat Methods . 2024 Nov; 22(1):124-134. PMID: 39587358
Disorder and flexibility in protein structures are essential for biological function but can also contribute to diseases, such as neurodegenerative disorders. However, characterizing protein folding on a proteome-wide scale within...
9.
Gentry-Torfer D, Murillo E, Barrington C, Nie S, Leeming M, Suwanchaikasem P, et al.
Bio Protoc . 2024 May; 14(9):e4981. PMID: 38737506
Ribosomes are an archetypal ribonucleoprotein assembly. Due to ribosomal evolution and function, r-proteins share specific physicochemical similarities, making the riboproteome particularly suited for tailored proteome profiling methods. Moreover, the structural...
10.
Dorney R, Johnston E, Karnaneedi S, Ruethers T, Kamath S, Gopi K, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38674116
Due to the widespread use of shellfish ingredients in food products, accurate food labelling is urgently needed for consumers with shellfish allergies. Most crustacean allergen detection systems target the immunorecognition...