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Neha Bhagwat

Explore the profile of Neha Bhagwat including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 2714
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Recent Articles
1.
Bewersdorf J, Mi X, Lu B, Kuykendall A, Sallman D, Patel M, et al.
Leukemia . 2025 Jan; 39(3):765-769. PMID: 39856223
No abstract available.
2.
Brown-Burke F, Saadey R, Mao H, Marra P, Brooks E, Wandtke A, et al.
Blood Adv . 2025 Jan; PMID: 39825858
Hemophagocytic lymphohistiocytosis (HLH) is a rare but aggressive and potentially lethal hyperinflammatory syndrome characterized by pathologic immune activation and excessive production of proinflammatory cytokines leading to tissue damage and multisystem...
3.
Till J, McDaniel L, Chang C, Long Q, Pfeiffer S, Lyman J, et al.
Nat Commun . 2024 Jul; 15(1):5763. PMID: 38982051
While high circulating tumor DNA (ctDNA) levels are associated with poor survival for multiple cancers, variant-specific differences in the association of ctDNA levels and survival have not been examined. Here...
4.
Fultang N, Schwab A, McAneny-Droz S, Grego A, Rodgers S, Torres B, et al.
Front Oncol . 2024 Feb; 14:1343004. PMID: 38371625
MCL1 is a member of the BCL2 family of apoptosis regulators, which play a critical role in promoting cancer survival and drug resistance. We previously described PRT1419, a potent, MCL1...
5.
Pritchard J, Pearce J, Snoeren I, Fuchs S, Gotz K, Peisker F, et al.
Cell Rep . 2023 Dec; 43(1):113608. PMID: 38117649
The role of hematopoietic Hedgehog signaling in myeloproliferative neoplasms (MPNs) remains incompletely understood despite data suggesting that Hedgehog (Hh) pathway inhibitors have therapeutic activity in patients. We aim to systematically...
6.
Carter J, Hulse M, Sivakumar M, Burtell J, Thodima V, Wang M, et al.
Cancer Res Commun . 2023 Oct; 3(11):2233-2243. PMID: 37861290
Significance: Patients with advanced cancers frequently develop resistance to chemotherapy or PARP inhibitors mainly due to circumvention and/or restoration of the inactivated DDR pathway genes. We demonstrate that inhibition of...
7.
Brown-Burke F, Hwang I, Sloan S, Hinterschied C, Helmig-Mason J, Long M, et al.
Blood Adv . 2023 Jun; 7(20):6211-6224. PMID: 37327122
Mantle cell lymphoma (MCL) is an incurable B-cell malignancy that comprises up to 6% of non-Hodgkin lymphomas diagnosed annually and is associated with a poor prognosis. The average overall survival...
8.
Pastore F, Bhagwat N, Pastore A, Radzisheuskaya A, Karzai A, Krishnan A, et al.
Cancer Discov . 2020 Jul; 10(11):1742-1757. PMID: 32669286
We investigated the role of PRMT5 in myeloproliferative neoplasm (MPN) pathogenesis and aimed to elucidate key PRMT5 targets contributing to MPN maintenance. PRMT5 is overexpressed in primary MPN cells, and...
9.
Yang Z, LaRiviere M, Ko J, Till J, Christensen T, Yee S, et al.
Clin Cancer Res . 2020 Apr; 26(13):3248-3258. PMID: 32299821
Purpose: To determine whether a multianalyte liquid biopsy can improve the detection and staging of pancreatic ductal adenocarcinoma (PDAC). Experimental Design: We analyzed plasma from 204 subjects (71 healthy, 44...
10.
Song J, Hegge J, Mauk M, Chen J, Till J, Bhagwat N, et al.
Nucleic Acids Res . 2019 Dec; 48(4):e19. PMID: 31828328
Detection of disease-associated, cell-free nucleic acids in body fluids enables early diagnostics, genotyping and personalized therapy, but is challenged by the low concentrations of clinically significant nucleic acids and their...