Nayef A Mazloum
Overview
Explore the profile of Nayef A Mazloum including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
334
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Recent Articles
1.
Almuraikhy S, Alser M, Naja K, Al-Malki A, Mazloum N, Elrayess M
Cells
. 2025 Jan;
14(2).
PMID: 39851528
GATA-3 is a master regulator of preadipocyte differentiation and function. Pharmacological or genetic targeting of GATA-3 will allow us to understand the function of GATA-3 in regulating metabolism, insulin signaling,...
2.
Vakayil M, Madani A, Agha M, Majeed Y, Hayat S, Yonuskunju S, et al.
Sci Rep
. 2024 May;
14(1):11886.
PMID: 38789534
The E3 ubiquitin-ligase UHRF1 is an epigenetic regulator coordinating DNA methylation and histone modifications. However, little is known about how it regulates adipogenesis or metabolism. In this study, we discovered...
3.
Wang X, Zhang S, Zhang Z, Mazloum N, Lee E, Lee M
DNA Repair (Amst)
. 2023 Jun;
128:103513.
PMID: 37285751
The extension of the invading strand within a displacement loop (D-loop) is a key step in homology directed repair (HDR) of doubled stranded DNA breaks. The primary goal of these...
4.
Majeed Y, Madani A, Altamimi A, Courjaret R, Vakayil M, Fountain S, et al.
Br J Pharmacol
. 2022 Nov;
180(5):609-627.
PMID: 36321760
Background And Purpose: Senescent preadipocytes promote adipose tissue dysfunction by secreting pro-inflammatory factors, although little is known about the mechanisms regulating their production. We investigated if up-regulated purinoceptor function sensitizes...
5.
Diboun I, Ramanjaneya M, Ahmed L, Bashir M, Butler A, Albagha O, et al.
Front Endocrinol (Lausanne)
. 2021 Jul;
12:638727.
PMID: 34211435
Background: Polycystic ovary syndrome (PCOS) is a complex syndrome with clinical features of an endocrine/metabolic disorder. Various metabolites show significant association with PCOS; however, studies comparing the metabolic profile of...
6.
Sellami M, Al-Muraikhy S, Al-Jaber H, Al-Amri H, Al-Mansoori L, Mazloum N, et al.
Antioxidants (Basel)
. 2021 Jul;
10(7).
PMID: 34203235
Background: Exercise-associated immune response plays a crucial role in the aging process. The aim of this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress...
7.
Majeed Y, Halabi N, Madani A, Engelke R, Bhagwat A, Abdesselem H, et al.
Sci Rep
. 2021 Apr;
11(1):8177.
PMID: 33854178
The NAD-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD boosters alleviate metabolic complications. We previously...
8.
Madani A, Majeed Y, Abdesselem H, Agha M, Vakayil M, Sukhun N, et al.
Antioxidants (Basel)
. 2021 Mar;
10(2).
PMID: 33672392
Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR),...
9.
Diboun I, Ramanjaneya M, Majeed Y, Ahmed L, Bashir M, Butler A, et al.
J Transl Med
. 2020 Sep;
18(1):366.
PMID: 32972433
Background: Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. In this study, metabolic profiling of...
10.
Al-Mansoori L, Al-Jaber H, Madani A, Mazloum N, Agouni A, Ramanjaneya M, et al.
Cell Signal
. 2020 Aug;
75:109735.
PMID: 32795510
Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important...