Yasser Majeed
Overview
Explore the profile of Yasser Majeed including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
1099
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Recent Articles
1.
Vakayil M, Madani A, Agha M, Majeed Y, Hayat S, Yonuskunju S, et al.
Sci Rep
. 2024 May;
14(1):11886.
PMID: 38789534
The E3 ubiquitin-ligase UHRF1 is an epigenetic regulator coordinating DNA methylation and histone modifications. However, little is known about how it regulates adipogenesis or metabolism. In this study, we discovered...
2.
Majeed Y, Madani A, Altamimi A, Courjaret R, Vakayil M, Fountain S, et al.
Br J Pharmacol
. 2022 Nov;
180(5):609-627.
PMID: 36321760
Background And Purpose: Senescent preadipocytes promote adipose tissue dysfunction by secreting pro-inflammatory factors, although little is known about the mechanisms regulating their production. We investigated if up-regulated purinoceptor function sensitizes...
3.
Majeed Y, Halabi N, Madani A, Engelke R, Bhagwat A, Abdesselem H, et al.
Sci Rep
. 2021 Apr;
11(1):8177.
PMID: 33854178
The NAD-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD boosters alleviate metabolic complications. We previously...
4.
Madani A, Majeed Y, Abdesselem H, Agha M, Vakayil M, Sukhun N, et al.
Antioxidants (Basel)
. 2021 Mar;
10(2).
PMID: 33672392
Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR),...
5.
Diboun I, Ramanjaneya M, Majeed Y, Ahmed L, Bashir M, Butler A, et al.
J Transl Med
. 2020 Sep;
18(1):366.
PMID: 32972433
Background: Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. In this study, metabolic profiling of...
6.
Samuel S, Satheesh N, Ghosh S, Busselberg D, Majeed Y, Ding H, et al.
Cancers (Basel)
. 2019 Nov;
11(11).
PMID: 31698699
Metformin, the most widely used anti-diabetic drug, also exhibits anti-cancer properties; however, the true potential of metformin as an anticancer drug remains largely unknown. In this study using mouse microvascular...
7.
Majeed Y, Upadhyay R, Alhousseiny S, Taha T, Musthak A, Shaheen Y, et al.
Sci Rep
. 2019 Apr;
9(1):6316.
PMID: 31004117
Angiosarcomas are highly aggressive tumors of endothelial origin, which carry a poor prognosis. Fenofibrate is a hypolipidemic drug, which acts by activating the transcription factor PPARα. It has also been...
8.
Samuel S, Ghosh S, Majeed Y, Arunachalam G, Emara M, Ding H, et al.
Biochem Pharmacol
. 2017 Mar;
132:118-132.
PMID: 28274614
Metformin, the most frequently administered drug for the treatment of type 2 diabetes, is being investigated for its potential in the treatment of various types of cancer; however, the cellular...
9.
Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow M, et al.
Nature
. 2014 Aug;
515(7526):279-282.
PMID: 25119035
The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic. Studies of sensory neurons have suggested Piezo proteins as subunits...
10.
Amer M, McKeown L, Tumova S, Liu R, Seymour V, Wilson L, et al.
Br J Pharmacol
. 2012 Nov;
168(6):1445-55.
PMID: 23121507
Background And Purpose: The Sigma-1 receptor (Sig1R) impacts on calcium ion signalling and has a plethora of ligands. This study investigated Sig1R and its ligands in relation to endogenous calcium...