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Raphael Courjaret

Explore the profile of Raphael Courjaret including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 366
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Recent Articles
1.
Yu F, Courjaret R, Assaf L, Elmi A, Hammad A, Fisher M, et al.
iScience . 2024 Mar; 27(4):109379. PMID: 38510124
Mitochondria-ER contact sites (MERCS) are involved in energy homeostasis, redox and Ca signaling, and inflammation. MERCS are heavily studied; however, little is known about their regulation during mitosis. Here, we...
2.
Courjaret R, Prakriya M, Machaca K
J Physiol . 2023 Apr; 602(8):1449-1462. PMID: 37029630
Store operated Ca entry (SOCE) is a ubiquitous signalling module with established roles in the immune system, secretion and muscle development. Recent evidence supports a complex role for SOCE in...
3.
Majeed Y, Madani A, Altamimi A, Courjaret R, Vakayil M, Fountain S, et al.
Br J Pharmacol . 2022 Nov; 180(5):609-627. PMID: 36321760
Background And Purpose: Senescent preadipocytes promote adipose tissue dysfunction by secreting pro-inflammatory factors, although little is known about the mechanisms regulating their production. We investigated if up-regulated purinoceptor function sensitizes...
4.
Yu F, Courjaret R, Elmi A, Adap E, Orie N, Zghyer F, et al.
J Physiol . 2022 Oct; 600(22):4827-4848. PMID: 36181482
Loss of function mutations in store-operated Ca entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role...
5.
Courjaret R, Machaca K
Cell Calcium . 2021 May; 97:102421. PMID: 34023656
Our current understanding of the molecular mechanisms underlying activation of store-operated Ca entry (SOCE) relies in large part on studies that modulate the expression of STIM1 and Orai1. Shen et...
6.
Majeed Y, Halabi N, Madani A, Engelke R, Bhagwat A, Abdesselem H, et al.
Sci Rep . 2021 Apr; 11(1):8177. PMID: 33854178
The NAD-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD boosters alleviate metabolic complications. We previously...
7.
Nader N, Dib M, Hodeify R, Courjaret R, Elmi A, Hammad A, et al.
PLoS Biol . 2021 Feb; 19(2):e3001117. PMID: 33566812
[This corrects the article DOI: 10.1371/journal.pbio.3000901.].
8.
Hodeify R, Dib M, Alcantara-Adap E, Courjaret R, Nader N, Reyes C, et al.
Sci Rep . 2021 Jan; 11(1):2290. PMID: 33504898
Regulation of Ca signaling is critical for the progression of cell division, especially during meiosis to prepare the egg for fertilization. The primary Ca influx pathway in oocytes is Store-Operated...
9.
Reddy Gandra U, Courjaret R, Machaca K, Al-Hashimi M, Bazzi H
Sci Rep . 2020 Nov; 10(1):19519. PMID: 33177560
There a few reports of rhodamine-based fluorescent sensors for selective detection of only Al, due to the challenge of identifying a suitable ligand for binding Al ion. The use of...
10.
Nader N, Dib M, Hodeify R, Courjaret R, Elmi A, Hammad A, et al.
PLoS Biol . 2020 Nov; 18(11):e3000901. PMID: 33137110
The steroid hormone progesterone (P4) mediates many physiological processes through either nuclear receptors that modulate gene expression or membrane P4 receptors (mPRs) that mediate nongenomic signaling. mPR signaling remains poorly...