Nathan Wlodarchak
Overview
Explore the profile of Nathan Wlodarchak including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
369
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wlodarchak N, Feltenberger J, Ye Z, Beczkiewicz J, Procknow R, Yan G, et al.
ACS Med Chem Lett
. 2022 Jan;
12(2):228-235.
PMID: 35035774
Tuberculosis is a major global public health concern, and new drugs are needed to combat both the typical form and the increasingly common drug-resistant form of this disease. The essential...
2.
Polubothu S, Zecchin D, Al-Olabi L, Lionarons D, Harland M, Horswell S, et al.
Genet Med
. 2021 Jun;
23(9):1636-1647.
PMID: 34145395
Purpose: Much of the heredity of melanoma remains unexplained. We sought predisposing germline copy-number variants using a rare disease approach. Methods: Whole-genome copy-number findings in patients with melanoma predisposition syndrome...
3.
Zhang H, Ericksen S, Lee C, Ananiev G, Wlodarchak N, Yu P, et al.
PLoS Comput Biol
. 2019 Aug;
15(8):e1006813.
PMID: 31381559
Prediction of compounds that are active against a desired biological target is a common step in drug discovery efforts. Virtual screening methods seek some active-enriched fraction of a library for...
4.
Wlodarchak N, Teachout N, Beczkiewicz J, Procknow R, Schaenzer A, Satyshur K, et al.
Mol Pharm
. 2018 Oct;
15(11):5410-5426.
PMID: 30285456
New tools and concepts are needed to combat antimicrobial resistance. Actinomycetes and firmicutes share several eukaryotic-like Ser/Thr kinases (eSTK) that offer antibiotic development opportunities, including PknB, an essential mycobacterial eSTK....
5.
Schaenzer A, Wlodarchak N, Drewry D, Zuercher W, Rose W, Ferrer C, et al.
ACS Infect Dis
. 2018 Jul;
4(10):1508-1518.
PMID: 30059625
As antibiotic resistance rises, there is a need for strategies such as antibiotic adjuvants to conserve already-established antibiotics. A family of bacterial kinases known as the penicillin-binding-protein and serine/threonine kinase-associated...
6.
Guo F, Wlodarchak N, Menden P, Xing Y
Methods Mol Biol
. 2017 Dec;
1788:73-88.
PMID: 29247302
Proteomics is a powerful approach for systematic identification and quantification of the entire proteome of a biological system (cell, tissue, organ, biological fluid, or organism) at specific time points (...
7.
Schaenzer A, Wlodarchak N, Drewry D, Zuercher W, Rose W, Striker R, et al.
J Biol Chem
. 2017 Aug;
292(41):17037-17045.
PMID: 28821610
Bacterial signaling systems such as protein kinases and quorum sensing have become increasingly attractive targets for the development of novel antimicrobial agents in a time of rising antibiotic resistance. The...
8.
Wlodarchak N, Tariq R, Striker R
Trends Cell Mol Biol
. 2016 Mar;
10:49-75.
PMID: 27011661
Targeting kinases with semi-selective kinase inhibitors is one of the most successful drug development strategies of the 21 century. Zebrafish have become an increasingly useful model for pharmaceutical development. Water-soluble...
9.
Wlodarchak N, Xing Y
Crit Rev Biochem Mol Biol
. 2016 Feb;
51(3):162-84.
PMID: 26906453
Protein phosphatase 2A (PP2A) plays a critical multi-faceted role in the regulation of the cell cycle. It is known to dephosphorylate over 300 substrates involved in the cell cycle, regulating...
10.
Weger-Lucarelli J, Aliota M, Wlodarchak N, Kamlangdee A, Swanson R, Osorio J
J Virol
. 2015 Dec;
90(5):2418-33.
PMID: 26676771
Unlabelled: Alphaviruses represent a diverse set of arboviruses, many of which are important pathogens. Chikungunya virus (CHIKV), an arthritis-inducing alphavirus, is the cause of a massive ongoing outbreak in the...