Naritoshi Shirata
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Explore the profile of Naritoshi Shirata including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
156
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Recent Articles
1.
Empitu M, Kikyo M, Shirata N, Yamada H, Makino S, Kadariswantiningsih I, et al.
J Am Soc Nephrol
. 2023 May;
34(7):1222-1239.
PMID: 37134307
Significance Statement: Nuclear translocation of dendrin is observed in injured podocytes, but the mechanism and its consequence are unknown. In nephropathy mouse models, dendrin ablation attenuates proteinuria, podocyte loss, and...
2.
Iijima T, Katoh M, Takedomi K, Yamamoto Y, Akatsuka H, Shirata N, et al.
J Med Chem
. 2022 Jun;
65(12):8127-8143.
PMID: 35652647
Overactivation of the mineralocorticoid receptor (MR) is involved in many diseases, such as hypertension, kidney disease, and heart failure. Thus, MR antagonists (MRAs) are expected to be beneficial to patients...
3.
Makino S, Shirata N, Trejo J, Yamamoto-Nonaka K, Yamada H, Miyake T, et al.
J Am Soc Nephrol
. 2021 Jan;
32(3):597-613.
PMID: 33510039
Background: The ubiquitin-proteasome system (UPS) and the autophagy-lysosomal system (APLS) are major intracellular degradation procedures. The importance of the APLS in podocytes is established, but the role of the UPS...
4.
Yamada H, Shirata N, Makino S, Miyake T, Trejo J, Yamamoto-Nonaka K, et al.
Kidney Int
. 2020 Nov;
99(2):382-395.
PMID: 33144214
Podocytes are highly specialized cells within the glomerulus that are essential for ultrafiltration. The slit diaphragm between the foot processes of podocytes functions as a final filtration barrier to prevent...
5.
Inazumi T, Yamada K, Shirata N, Sato H, Taketomi Y, Morita K, et al.
Cell Rep
. 2020 Oct;
33(2):108265.
PMID: 33053354
Lipolysis, the breakdown of triglyceride storage in white adipose tissue, supplies fatty acids to other tissues as a fuel under fasting conditions. In morbid obesity, fibrosis limits adipocyte expandability, resulting...
6.
Shirata N, Ihara K, Yamamoto-Nonaka K, Seki T, Makino S, Trejo J, et al.
J Am Soc Nephrol
. 2017 May;
28(9):2654-2669.
PMID: 28539383
Membrane-associated guanylate kinase inverted 2 (MAGI-2) is a component of the slit diaphragm (SD) of glomerular podocytes. Here, we investigated the podocyte-specific function of MAGI-2 using newly generated podocyte-specific MAGI-2-knockout...
7.
Morimoto K, Shirata N, Taketomi Y, Tsuchiya S, Segi-Nishida E, Inazumi T, et al.
J Immunol
. 2013 Dec;
192(3):1130-7.
PMID: 24342806
PGE2 has long been known as a potentiator of acute inflammation, but its mechanisms of action still remain to be defined. In this study, we employed inflammatory swelling induced in...
8.
Inazumi T, Shirata N, Morimoto K, Takano H, Segi-Nishida E, Sugimoto Y
J Lipid Res
. 2011 Jun;
52(8):1500-8.
PMID: 21646392
The prostaglandin (PG) receptors EP4 and FP have the potential to exert negative effects on adipogenesis, but the exact contribution of endogenous PG-driven receptor signaling to this process is not...
9.
Takano H, Nakazawa S, Shirata N, Tamba S, Furuta K, Tsuchiya S, et al.
Lab Invest
. 2009 Feb;
89(4):446-55.
PMID: 19204665
By using the recently established culture system that reproduces the terminal differentiation process of connective tissue-type mast cells, we found significant transcriptional induction of CD44. As CD44 is a primary...
10.
Takano H, Nakazawa S, Okuno Y, Shirata N, Tsuchiya S, Kainoh T, et al.
FEBS Lett
. 2008 Apr;
582(10):1444-50.
PMID: 18381075
To understand physiological roles of tissue mast cells, we established a culture system where bone marrow-derived immature mast cells differentiate into the connective tissue-type mast cell (CTMC)-like cells through modifying...