Naohiro Yamaguchi
Overview
Explore the profile of Naohiro Yamaguchi including associated specialties, affiliations and a list of published articles.
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55
Citations
1223
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Recent Articles
1.
Chirasani V, Elferdink M, Kral M, Carter J, Heitmann S, Meissner G, et al.
J Biol Chem
. 2023 Dec;
300(2):105606.
PMID: 38159862
Previous cryo-electron micrographs suggested that the skeletal muscle Ca release channel, ryanodine receptor (RyR)1, is regulated by intricate interactions between the EF hand Ca binding domain and the cytosolic loop...
2.
Xia Y, Zhang X, Yamaguchi N, Morad M
Cardiovasc Res
. 2023 Oct;
120(1):44-55.
PMID: 37890099
Aims: CRISPR/Cas9 gene edits of cardiac ryanodine receptor (RyR2) in human-induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) provide a novel platform for introducing mutations in RyR2 Ca2+-binding residues and examining...
3.
Yamaguchi N, Zhang X, Morad M
Methods Mol Biol
. 2022 Aug;
2573:41-52.
PMID: 36040585
Human-induced pluripotent stem cells (hiPSCs) provide a powerful platform to study biophysical and molecular mechanisms underlying the pathophysiology of genetic mutations associated with cardiac arrhythmia. Human iPSCs can be generated...
4.
5.
Oishi M, Mukaino A, Kunii M, Saito A, Arita Y, Koike H, et al.
J Neurol
. 2021 Apr;
268(11):4265-4279.
PMID: 33881596
Objective: To determine whether autonomic dysfunction in neurosarcoidosis is associated with anti-ganglionic acetylcholine receptor (gAChR) antibodies, which are detected in autoimmune autonomic ganglionopathy. Methods: We retrospectively extracted cases of sarcoidosis...
6.
Fuse T, Nakagaki T, Homma T, Tange H, Yamaguchi N, Atarashi R, et al.
Neurosci Res
. 2021 Jan;
171:34-40.
PMID: 33476681
The defining characteristic of prion diseases is conversion of a cellular prion protein (PrP) to an abnormal prion protein (PrP). The exogenous attachment of PrP to the surface of a...
7.
Yonezawa K, Kusumoto Y, Kanchi N, Kinoshita H, Kanegae S, Yamaguchi N, et al.
J Neural Transm (Vienna)
. 2020 May;
127(11):1491-1499.
PMID: 32451632
Although it is clear that nutrition affects physical and metabolic functions in humans, the importance of nutrition in mental illness has often been overlooked. Following a report by Hibbeln (Lancet...
8.
Matsubara T, Satoh K, Homma T, Nakagaki T, Yamaguchi N, Atarashi R, et al.
Biochem Biophys Res Commun
. 2020 Feb;
525(2):447-454.
PMID: 32107004
Cellular prion protein (PrP) is a membrane protein that is highly conserved among mammals and mainly expressed on the cell surface of neurons. Despite its reported interactions with various membrane...
9.
Yamaguchi N
Adv Exp Med Biol
. 2019 Oct;
1131:321-336.
PMID: 31646516
Ryanodine receptor calcium release channels (RyRs) play central roles in controlling intracellular calcium concentrations in excitable and non-excitable cells. RyRs are located in the sarcoplasmic or endoplasmic reticulum, intracellular Ca...
10.
Chirasani V, Xu L, Addis H, Pasek D, Dokholyan N, Meissner G, et al.
Am J Physiol Cell Physiol
. 2019 Jun;
317(2):C358-C365.
PMID: 31166712
Cryoelectron microscopy and mutational analyses have shown that type 1 ryanodine receptor (RyR1) amino acid residues RyR1-E3893, -E3967, and -T5001 are critical for Ca-mediated activation of skeletal muscle Ca release...