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Nallathamby Devasahayam

Explore the profile of Nallathamby Devasahayam including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 969
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Recent Articles
1.
Kishimoto S, Horie K, Devasahayam N, Yamashita K, Gadisetti C, Yamamoto K, et al.
bioRxiv . 2025 Feb; PMID: 39896573
Renal oxygenation is essential for maintaining kidney function. Disruptions in oxygen delivery can lead to renal hypoxia, which can exacerbate kidney injury through multiple pathways, including inflammation, oxidative stress, and...
2.
Kishimoto S, Devasahayam N, Chandramouli G, Murugesan R, Otowa Y, Yamashita K, et al.
Magn Reson Med . 2023 Sep; 91(1):413-423. PMID: 37676121
Purpose: In this study, we compared two triarylmethyl (TAM) spin probes, Ox071 and Ox063 for their efficacy in measuring tissue oxygen levels under hypoxic and normoxic conditions by R *-based...
3.
Otowa Y, Kishimoto S, Saida Y, Yamashita K, Yamamoto K, Chandramouli G, et al.
Antioxid Redox Signal . 2023 Apr; 39(7-9):432-444. PMID: 37051681
Pancreatic ductal adenocarcinomas (PDACs) form hypovascular and hypoxic tumors, which are difficult to treat with current chemotherapy regimens. Gemcitabine (GEM) is often used as a first-line treatment for PDACs but...
4.
Kawai T, Matsuo M, Takakusagi Y, Saito K, Hyodo F, Devasahayam N, et al.
NMR Biomed . 2022 Jun; 35(10):e4783. PMID: 35661282
Reoxygenation has a significant impact on the tumor response to radiotherapy. With developments in radiotherapy technology, the relevance of the reoxygenation phenomenon in treatment efficacy has been a topic of...
5.
Seki T, Saida Y, Kishimoto S, Lee J, Otowa Y, Yamamoto K, et al.
Neoplasia . 2022 May; 30:100793. PMID: 35523073
Purpose: PEGylated human hyaluronidase (PEGPH20) enzymatically depletes hyaluronan, an important component of the extracellular matrix, increasing the delivery of therapeutic molecules. Combinations of chemotherapy and PEGPH20, however, have been unsuccessful...
6.
Brender J, Saida Y, Devasahayam N, Krishna M, Kishimoto S
Antioxid Redox Signal . 2021 Aug; 36(1-3):144-159. PMID: 34428981
Oxygen imaging techniques, which can probe the spatiotemporal heterogeneity of tumor oxygenation, could be of significant clinical utility in radiation treatment planning and in evaluating the effectiveness of hypoxia-activated prodrugs....
7.
Yamamoto K, Brender J, Seki T, Kishimoto S, Oshima N, Choudhuri R, et al.
Cancer Res . 2020 Apr; 80(11):2087-2093. PMID: 32245793
Molecular imaging approaches for metabolic and physiologic imaging of tumors have become important for treatment planning and response monitoring. However, the relationship between the physiologic and metabolic aspects of tumors...
8.
Pursley R, Enomoto A, Wu H, Brender J, Pohida T, Subramanian S, et al.
J Magn Reson . 2018 Dec; 299:42-48. PMID: 30579225
An excessive RF power requirement is one of the main obstacles in the clinical translation of EPR imaging. The radio frequency (RF) pulses used in EPR imaging to excite electron...
9.
Read G, Miura N, Carter J, Kines K, Yamamoto K, Devasahayam N, et al.
Colloids Surf B Biointerfaces . 2018 Jul; 171:197-204. PMID: 30031304
The purpose of this study is to demonstrate calcium alginate hydrogels as a system for in vitro radiobiological and metabolic studies of cancer cells. Previous studies have established calcium alginate...
10.
Matsuo M, Kawai T, Kishimoto S, Saito K, Munasinghe J, Devasahayam N, et al.
Oncotarget . 2018 Jun; 9(38):25089-25100. PMID: 29861855
To examine the relationship between local oxygen partial pressure and energy metabolism in the tumor, electron paramagnetic resonance imaging (EPRI) and magnetic resonance imaging (MRI) with hyperpolarized [1-C] pyruvate were...