Jeeva P Munasinghe
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Explore the profile of Jeeva P Munasinghe including associated specialties, affiliations and a list of published articles.
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24
Citations
612
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Recent Articles
1.
Lookian P, Chandrashekhar V, Cappadona A, Bryant J, Chandrashekhar V, Tunacao J, et al.
JCI Insight
. 2021 Sep;
6(21).
PMID: 34546977
We recently described a transtentorial venous system (TTVS), which to our knowledge was previously unknown, connecting venous drainage throughout the brain in humans. Prior to this finding, it was believed...
2.
Rosenblum J, Cappadona A, Argersinger D, Pang Y, Wang H, Nazari M, et al.
Neurol Genet
. 2020 Apr;
6(3):e414.
PMID: 32337341
Objective: To investigate the effect of somatic, postzygotic, gain-of-function mutation of Endothelial Per-Arnt-Sim (PAS) domain protein 1 () encoding hypoxia-inducible factor-2α (HIF-2α) on posterior fossa development and spinal dysraphism in...
3.
Tona R, Chen W, Nakano Y, Reyes L, Petralia R, Wang Y, et al.
Hum Mol Genet
. 2019 Jan;
28(9):1530-1547.
PMID: 30602030
Epilepsy, deafness, onychodystrophy, osteodystrophy and intellectual disability are associated with a spectrum of mutations of human TBC1D24. The mechanisms underlying TBC1D24-associated disorders and the functions of TBC1D24 are not well...
4.
Riggle B, Sinharay S, Schreiber-Stainthorp W, Munasinghe J, Maric D, Prchalova E, et al.
Proc Natl Acad Sci U S A
. 2018 Dec;
115(51):E12024-E12033.
PMID: 30514812
The deadliest complication of infection is cerebral malaria (CM), with a case fatality rate of 15 to 25% in African children despite effective antimalarial chemotherapy. No adjunctive treatments are yet...
5.
Takakusagi Y, Naz S, Takakusagi K, Ishima M, Murata H, Ohta K, et al.
Cancer Res
. 2018 Oct;
78(24):6828-6837.
PMID: 30301838
: Hypoxic zones in solid tumors contribute to radioresistance, and pharmacologic agents that increase tumor oxygenation prior to radiation, including antiangiogenic drugs, can enhance treatment response to radiotherapy. Although such...
6.
Matsumoto S, Kishimoto S, Saito K, Takakusagi Y, Munasinghe J, Devasahayam N, et al.
Cancer Res
. 2018 May;
78(14):3783-3792.
PMID: 29792309
Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxic niches that lead to treatment resistance. Therefore, studies of tumor oxygenation and metabolic profiling should contribute to improved treatment strategies. Here, we...
7.
Scroggins B, Matsuo M, White A, Saito K, Munasinghe J, Sourbier C, et al.
Clin Cancer Res
. 2018 Mar;
24(13):3137-3148.
PMID: 29599412
To evaluate the potential of hyperpolarized [1-C]-pyruvate magnetic resonance spectroscopic imaging (MRSI) of prostate cancer as a predictive biomarker for targeting the Warburg effect. Two human prostate cancer cell lines...
8.
Tu T, Ibrahim W, Jikaria N, Munasinghe J, Witko J, Hammoud D, et al.
Sci Rep
. 2018 Jan;
8(1):669.
PMID: 29330386
Metabolic abnormalities are commonly observed in traumatic brain injury (TBI) patients exhibiting long-term neurological deficits. This study investigated the feasibility and reproducibility of using chemical exchange saturation transfer (CEST) MRI...
9.
Yang X, Liu Z, Zhang H, Li Z, Munasinghe J, Niu G, et al.
Eur J Nucl Med Mol Imaging
. 2017 Dec;
45(4):585-592.
PMID: 29285548
Purpose: C-methionine (MET) is one of the most commonly used amino acid tracers for PET imaging of brain tumors. In this study, we report an F-labeled boron-derived methionine analogue, denoted...
10.
Kawabata S, Hollander M, Munasinghe J, Brinster L, Mercado-Matos J, Li J, et al.
Oncotarget
. 2015 Jun;
6(13):11357-68.
PMID: 26027747
Adenomatous tumors in the middle ear and temporal bone are rare but highly morbid because they are difficult to detect prior to the development of audiovestibular dysfunction. Complete resection is...