Nagasuma Chandra
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Explore the profile of Nagasuma Chandra including associated specialties, affiliations and a list of published articles.
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129
Citations
1514
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Recent Articles
1.
Regenerative agriculture augments bacterial community structure for a healthier soil and agriculture
Singh I, Hussain M, Manjunath G, Chandra N, Ravikanth G
Front Agron
. 2024 Jul;
5:1134514.
PMID: 39071943
Introduction: Use of chemical fertilization and pesticides not only harm the environment but also have detrimental consequences on human health. In recent years, there has been a major emphasis worldwide...
2.
Banerjee U, Borbora S, Guha M, Yadav V, Sanjay V, Singh A, et al.
Immunology
. 2024 Mar;
172(3):392-407.
PMID: 38504502
Treatment of tuberculosis (TB) is faced with several challenges including the long treatment duration, drug toxicity and tissue pathology. Host-directed therapy provides promising avenues to find compounds for adjunctively assisting...
3.
Sankar S, Vasudevan S, Chandra N
Structure
. 2024 Jan;
32(3):362-375.e4.
PMID: 38194962
While predicting a ligand that binds to a protein is feasible with current methods, the opposite, i.e., the prediction of a receptor for a ligand remains challenging. We present an...
4.
Sankar S, Preeti P, Ravikumar K, Kumar A, Prasad Y, Pal S, et al.
Curr Res Struct Biol
. 2023 Dec;
6:100108.
PMID: 38106461
S-adenosylmethionine (SAM) is a ubiquitous co-factor that serves as a donor for methylation reactions and additionally serves as a donor of other functional groups such as amino and ribosyl moieties...
5.
Das M, Sreedharan S, Shee S, Malhotra N, Nandy M, Banerjee U, et al.
Sci Adv
. 2023 Dec;
9(50):eadh2858.
PMID: 38091389
Iron-sulfur (Fe-S) biogenesis requires multiprotein assembly systems, SUF and ISC, in most prokaryotes. () encodes a complete SUF system, the depletion of which was bactericidal. The ISC operon is truncated...
6.
Kavitha B, Srikanth K, Singh D, Gopi S, Mohan V, Chandra N, et al.
Acta Diabetol
. 2023 Oct;
61(2):189-194.
PMID: 37821536
Aim: To identify the genetic etiology of neonatal diabetes in an infant and to elucidate the molecular mechanism of the identified mutation underlying the pathogenesis. Methods: Genetic analysis was carried...
7.
Banerjee U, Chedere A, Padaki R, Mohan A, Sambaturu N, Singh A, et al.
J Chem Inf Model
. 2023 Sep;
63(19):6156-6167.
PMID: 37756209
Mining large-scale data to discover biologically relevant information remains a challenge despite the rapid development of bioinformatics tools. Here, we have developed a new tool, PathTracer, to identify biologically relevant...
8.
Shee S, Veetil R, Mohanraj K, Das M, Malhotra N, Bandopadhyay D, et al.
Elife
. 2023 Aug;
12.
PMID: 37642294
() is evolutionarily equipped to resist exogenous reactive oxygen species (ROS) but shows vulnerability to an increase in endogenous ROS (eROS). Since eROS is an unavoidable consequence of aerobic metabolism,...
9.
Banerjee U, Chunchanur S, R A, Balaji K, Singh A, Chakravortty D, et al.
Genes Immun
. 2023 Jul;
24(4):183-193.
PMID: 37438430
Host immune response to COVID-19 plays a significant role in regulating disease severity. Although big data analysis has provided significant insights into the host biology of COVID-19 across the world,...
10.
Identification of Probucol as a candidate for combination therapy with Metformin for Type 2 diabetes
Guttapadu R, Korla K, Uk S, Annam V, Ashok P, Chandra N
NPJ Syst Biol Appl
. 2023 May;
9(1):18.
PMID: 37221264
Type 2 Diabetes (T2D) is often managed with metformin as the drug of choice. While it is effective overall, many patients progress to exhibit complications. Strategic drug combinations to tackle...