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Nagasuma Chandra

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Articles 129
Citations 1514
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Recent Articles
11.
Rao V, Banerjee U, Sambaturu N, Chunchanur S, Ambica R, Chandra N
HLA . 2023 May; 102(4):464-476. PMID: 37134008
Heterogeneity in susceptibility among individuals to COVID-19 has been evident through the pandemic worldwide. Cytotoxic T lymphocyte (CTL) responses generated against pathogens in certain individuals are known to impose selection...
12.
Guttapadu R, Prakash N, M A, Chatterjee R, S M, M J, et al.
PLoS Negl Trop Dis . 2023 Apr; 17(4):e0011263. PMID: 37018379
Rheumatic heart disease (RHD) continues to affect developing countries with low income due to the lack of resources and effective diagnostic techniques. Understanding the genetic basis common to both the...
13.
Chatterjee R, Roy Chowdhury A, Nair A, Hajra D, Kar A, Datey A, et al.
Microbiol Res . 2023 Mar; 271:127351. PMID: 36931126
Salmonella enterica serovar Typhimurium is a common cause of gastroenteritis in humans and occasionally causes systemic infection. Salmonella's ability to survive and replicate within macrophages is an important characteristic during...
14.
Chedere A, Mishra M, Kulkarni O, Sriraman S, Chandra N
Front Oncol . 2022 Oct; 12:954512. PMID: 36249025
Cancer cells are known to undergo metabolic adaptation to cater to their enhanced energy demand. Nicotinamide adenine dinucleotide (NAD) is an essential metabolite regulating many cellular processes within the cell....
15.
Rao V, Chandra N
Hum Immunol . 2022 Oct; 83(12):797-802. PMID: 36229378
Differences in outcome to COVID-19 infection in different individuals is largely attributed to genetic heterogeneity leading to differential immune responses across individuals and populations. HLA is one such genetic factor...
16.
Sankar S, Chandran Sakthivel N, Chandra N
J Chem Inf Model . 2022 Sep; 62(19):4810-4819. PMID: 36122166
Protein function is a direct consequence of its sequence, structure, and the arrangement at the binding site. Bioinformatics using sequence analysis is typically used to gain a first insight into...
17.
Shee S, Singh S, Tripathi A, Thakur C, Kumar T A, Das M, et al.
Antimicrob Agents Chemother . 2022 Aug; 66(9):e0059222. PMID: 35975988
Moxifloxacin is central to treatment of multidrug-resistant tuberculosis. Effects of moxifloxacin on the Mycobacterium tuberculosis redox state were explored to identify strategies for increasing lethality and reducing the prevalence of...
18.
Banerjee U, Rao P, Reddy M, Hussain M, Chunchanur S, Ambica R, et al.
Mol Omics . 2022 Aug; 18(8):814-820. PMID: 35971789
Confirmatory diagnosis of bacterial coinfections with COVID-19 is challenging due to the limited specificity of the widely used gold-standard culture sensitivity test despite clinical presentations. A misdiagnosis can either lead...
19.
Tripathi A, Anand K, Das M, ONiel R, P S S, Thakur C, et al.
PLoS Pathog . 2022 Apr; 18(4):e1010475. PMID: 35427399
Iron-sulfur (Fe-S) cluster proteins carry out essential cellular functions in diverse organisms, including the human pathogen Mycobacterium tuberculosis (Mtb). The mechanisms underlying Fe-S cluster biogenesis are poorly defined in Mtb....
20.
Chattopadhyay G, Bhasin M, Ahmed S, Gosain T, Ganesan S, Das S, et al.
J Bacteriol . 2022 Mar; 204(4):e0005822. PMID: 35357163
The Mycobacterium tuberculosis genome harbors nine toxin-antitoxin (TA) systems that are members of the family, unlike other prokaryotes, which have only one or two. Although the overall tertiary folds of...