Nada A Abumrad
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Explore the profile of Nada A Abumrad including associated specialties, affiliations and a list of published articles.
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121
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Recent Articles
1.
Shibao C, Peche V, Pietka T, Samovski D, Williams I, Abumrad N, et al.
Diabetologia
. 2024 Nov;
68(3):662-675.
PMID: 39503770
Aims/hypothesis: Microvascular dysfunction contributes to insulin resistance. CD36, a fatty acid transporter and modulator of insulin signalling, is abundant in microvascular endothelial cells. Humans carrying the minor allele (G) of...
2.
Schleh M, Ryan B, Ahn C, Ludzki A, Van Pelt D, Pitchford L, et al.
Acta Physiol (Oxf)
. 2024 Nov;
241(1):e14249.
PMID: 39487600
Aim: To examine factors underlying why most, but not all, adults with obesity exhibit impaired insulin-mediated glucose uptake, we compared: (1) adipose tissue fatty acid (FA) release, (2) skeletal muscle...
3.
Srivastava N, Hu H, Peterson O, Vomund A, Stremska M, Zaman M, et al.
Immunity
. 2024 May;
57(7):1629-1647.e8.
PMID: 38754432
The pancreatic islet microenvironment is highly oxidative, rendering β cells vulnerable to autoinflammatory insults. Here, we examined the role of islet resident macrophages in the autoimmune attack that initiates type...
4.
Microvascular insulin resistance associates with enhanced muscle glucose disposal in CD36 deficiency
Shibao C, Peche V, Williams I, Samovski D, Pietka T, Abumrad N, et al.
medRxiv
. 2024 Feb;
PMID: 38405702
Dysfunction of endothelial insulin delivery to muscle associates with insulin resistance. CD36, a fatty acid transporter and modulator of insulin signaling is abundant in endothelial cells, especially in capillaries. Humans...
5.
Pietka T, Abumrad N
Methods Mol Biol
. 2023 Apr;
2662:33-52.
PMID: 37076669
Dysfunction in adipocyte expansion during the onset of obesity is associated with metabolic abnormalities. Determination of adipocyte size and number is an important measure for a comprehensive evaluation of the...
6.
Samovski D, Jacome-Sosa M, Abumrad N
Annu Rev Physiol
. 2022 Nov;
85:317-337.
PMID: 36347219
Long-chain fatty acids (FAs) are components of plasma membranes and an efficient fuel source and also serve as metabolic regulators through FA signaling mediated by membrane FA receptors. Impaired tissue...
7.
Borcherding N, Jia W, Giwa R, Field R, Moley J, Kopecky B, et al.
Cell Metab
. 2022 Sep;
34(10):1499-1513.e8.
PMID: 36070756
Adipocytes transfer mitochondria to macrophages in white and brown adipose tissues to maintain metabolic homeostasis. In obesity, adipocyte-to-macrophage mitochondria transfer is impaired, and instead, adipocytes release mitochondria into the blood...
8.
Cifarelli V, Kuda O, Yang K, Liu X, Gross R, Pietka T, et al.
Front Cardiovasc Med
. 2022 Sep;
9:948332.
PMID: 36061565
CD36 mediates the uptake of long-chain fatty acids (FAs), a major energy substrate for the myocardium. Under excessive FA supply, CD36 can cause cardiac lipid accumulation and inflammation while its...
9.
Cifarelli V, Peche V, Abumrad N
Biochim Biophys Acta Mol Cell Biol Lipids
. 2022 Jul;
1867(11):159207.
PMID: 35882297
The vascular and lymphatic systems in the gut regulate lipid transport while restricting transfer of commensal gut microbiota and directing immune cell trafficking. Increased permeability of the endothelial systems in...
10.
Jacome-Sosa M, Miao Z, Peche V, Morris E, Narendran R, Pietka K, et al.
Commun Biol
. 2021 Nov;
4(1):1247.
PMID: 34728772
The gastric epithelium is often exposed to injurious elements and failure of appropriate healing predisposes to ulcers, hemorrhage, and ultimately cancer. We examined the gastric function of CD36, a protein...