N Tony Eissa
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Explore the profile of N Tony Eissa including associated specialties, affiliations and a list of published articles.
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59
Citations
9957
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Recent Articles
21.
Bhattacharya A, Eissa N
Int Rev Immunol
. 2015 Feb;
34(5):382-402.
PMID: 25699578
Macroautophagy, hereafter, referred to as autophagy, has long been regarded as a housekeeping pathway involved in intracellular degradation and energy recycling. These housekeeping and homeostatic functions are especially important during...
22.
Bhattacharya A, Prakash Y, Eissa N
Cell Microbiol
. 2014 Sep;
16(11):1637-45.
PMID: 25237740
Eukaryotic cells utilize two main secretory pathways to transport proteins to the extracellular space. Proteins with a leader signal sequence often undergo co-translational transport into the endoplasmic reticulum (ER), and...
23.
Bhattacharya A, Parillon X, Zeng S, Han S, Eissa N
J Biol Chem
. 2014 Aug;
289(38):26525-26532.
PMID: 25077962
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) in the immune system. DCs present antigens to CD8 and CD4 T cells in the context of class I or...
24.
Tyryshkin A, Bhattacharya A, Eissa N
Cancer Res
. 2014 Apr;
74(7):1996-2005.
PMID: 24691995
Lymphangioleiomyomatosis (LAM) is a progressive cystic lung disease affecting some women with tuberous sclerosis complex (TSC). Sporadic LAM can develop in women without TSC, owing to somatic mutations in the...
25.
Xu Y, Abdel Fattah E, Liu X, Jagannath C, Eissa N
Tuberculosis (Edinb)
. 2014 Jan;
93 Suppl:S33-7.
PMID: 24388647
Autophagy, an evolutionary highly conserved process in virtually all eukaryotic cells, involves the sequestration of cytosol regions within double-membrane bound compartments and delivery of the contents to the lysosomes for...
26.
Wei Q, Sha Y, Bhattacharya A, Abdel Fattah E, Bonilla D, Jyothula S, et al.
Am J Respir Crit Care Med
. 2013 Nov;
189(1):16-29.
PMID: 24251647
Rationale: IL-4Rα, the common receptor component for IL-4 and IL-13, plays a critical role in IL-4- and IL-13-mediated signaling pathways that regulate airway inflammation and remodeling. However, the regulatory mechanisms...
27.
Shin J, Abdel Fattah E, Bhattacharya A, Ko S, Eissa N
J Biol Chem
. 2013 Nov;
288(50):35886-95.
PMID: 24178293
The association between altered proteostasis and inflammatory disorders has been increasingly recognized, but the underlying mechanisms are not well understood. In this study, we show that deficiency of either autophagy...
28.
Bonilla D, Bhattacharya A, Sha Y, Xu Y, Xiang Q, Kan A, et al.
Immunity
. 2013 Sep;
39(3):537-47.
PMID: 24035364
Autophagy and phagocytosis are conserved cellular functions involved in innate immunity. However, the nature of their interactions remains unclear. We evaluated the role of autophagy in regulating phagocytosis in macrophages...
29.
Bhattacharya A, Eissa N
Front Immunol
. 2013 Apr;
4:88.
PMID: 23596443
Autophagy, initially viewed as a conserved bulk-degradation mechanism, has emerged as a central player in a multitude of immune functions. Autophagy is important in host defense against intracellular and extracellular...
30.