Chinnaswamy Jagannath
Overview
Explore the profile of Chinnaswamy Jagannath including associated specialties, affiliations and a list of published articles.
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75
Citations
6172
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Recent Articles
1.
Singh D, Ahmed M, Akter S, Shivanna V, Bucsan A, Mishra A, et al.
Nat Commun
. 2025 Feb;
16(1):1957.
PMID: 40000643
The need for novel vaccination strategies to control tuberculosis (TB) is underscored by the limited and variable efficacy of the currently licensed vaccine, Bacille Calmette-Guerin (BCG). SigH is critical for...
2.
Steinmetz A, Pierce M, Martini A, Tholomier C, Manyam G, Chen Y, et al.
Front Immunol
. 2024 Nov;
15:1387229.
PMID: 39559365
Introduction: Nadofaragene firadenovec (Ad-IFNα/Syn3) is now approved for BCG-unresponsive bladder cancer (BLCA). IFNα is a pleiotropic cytokine that causes direct tumor cell killing via TRAIL-mediated apoptosis, angiogenesis inhibition, and activation...
3.
Singh V, Mishra A, Truong K, Bohorquez J, Sharma S, Khan A, et al.
bioRxiv
. 2024 Nov;
PMID: 39553987
Coinfections with (Mtb) and HIV-1 present a critical health challenge and require treatment for survival. We found that human M1 macrophages inhibit Mtb growth, while M2 macrophages, characterized by elevated...
4.
Bohorquez J, Jagannath C, Xu H, Wang X, Yi G
Vaccines (Basel)
. 2024 Aug;
12(8).
PMID: 39204027
Coinfection with () and the human immunodeficiency virus (HIV) is a significant public health concern. Individuals infected with who acquire HIV are approximately 16 times more likely to develop active...
5.
Mishra A, Khan A, Singh V, Glyde E, Saikolappan S, Garnica O, et al.
Front Immunol
. 2024 Jul;
15:1321657.
PMID: 38975346
Tuberculosis (TB) remains a significant global health challenge, with approximately 1.5 million deaths per year. The Bacillus Calmette-Guérin (BCG) vaccine against TB is used in infants but shows variable protection....
6.
Bohorquez J, Adduri S, Ansari D, John S, Florence J, Adejare O, et al.
Front Immunol
. 2024 May;
15:1395018.
PMID: 38799434
Background: Tuberculosis (TB), caused by (), continues to be a major public health problem worldwide. The human immunodeficiency virus (HIV) is another equally important life-threatening pathogen. HIV infection decreases CD4+...
7.
Veerapandian R, Gadad S, Jagannath C, Dhandayuthapani S
Vaccines (Basel)
. 2024 May;
12(5).
PMID: 38793781
Tuberculosis (TB), a chronic infectious disease affecting humans, causes over 1.3 million deaths per year throughout the world. The current preventive vaccine BCG provides protection against childhood TB, but it...
8.
Zhang K, Mishra A, Jagannath C
Front Immunol
. 2024 Apr;
15:1363938.
PMID: 38605962
Arginine and tryptophan are pivotal in orchestrating cytokine-driven macrophage polarization and immune activation. Specifically, interferon-gamma (IFN-γ) stimulates inducible nitric oxide synthase (iNOS) expression), leading to the conversion of arginine into...
9.
Bohorquez J, Adduri S, Ansari D, John S, Florence J, Adejare O, et al.
bioRxiv
. 2024 Mar;
PMID: 38496484
Tuberculosis (TB), caused by (), continues to be a major public health problem worldwide. The human immunodeficiency virus (HIV) is another equally important life-threatening pathogen. Further, co-infections with HIV and...
10.
Sayedahmed E, Elshafie N, Dos Santos A, Jagannath C, Sambhara S, Mittal S
Vaccines (Basel)
. 2024 Feb;
12(2).
PMID: 38400140
The nucleoprotein (NP) is a vital target for the heterosubtypic immunity of CD8 cytotoxic T lymphocytes (CTLs) due to its conservation among influenza virus subtypes. To further enhance the T...