Myat Lin Oo
Overview
Explore the profile of Myat Lin Oo including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
844
Followers
0
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Recent Articles
1.
Rumah K, Ma Y, Linden J, Oo M, Anrather J, Schaeren-Wiemers N, et al.
PLoS Pathog
. 2015 May;
11(5):e1004896.
PMID: 25993478
Clostridium perfringens ε-toxin (ETX) is a potent pore-forming toxin responsible for a central nervous system (CNS) disease in ruminant animals with characteristics of blood-brain barrier (BBB) dysfunction and white matter...
2.
Oo M, Chang S, Thangada S, Wu M, Rezaul K, Blaho V, et al.
J Clin Invest
. 2011 May;
121(6):2290-300.
PMID: 21555855
GPCR inhibitors are highly prevalent in modern therapeutics. However, interference with complex GPCR regulatory mechanisms leads to both therapeutic efficacy and adverse effects. Recently, the sphingosine-1-phosphate (S1P) receptor inhibitor FTY720...
3.
Thangada S, Khanna K, Blaho V, Oo M, Im D, Guo C, et al.
J Exp Med
. 2010 Jun;
207(7):1475-83.
PMID: 20584883
The sphingosine 1-phosphate receptor 1 (S1P(1)) promotes lymphocyte egress from lymphoid organs. Previous work showed that agonist-induced internalization of this G protein-coupled receptor correlates with inhibition of lymphocyte egress and...
4.
Hla T, Oo M
J Clin Invest
. 2009 Dec;
120(1):90-2.
PMID: 20038805
Arterial injury results in the formation of neointimal lesions. Lack of resolution of the pathologic neointima leads to stenosis, tissue ischemia, and organ dysfunction. In this issue of the JCI,...
5.
Yu M, Ohira M, Li Y, Niizuma H, Oo M, Zhu Y, et al.
Int J Oncol
. 2009 Mar;
34(4):931-8.
PMID: 19287950
Neuroblastoma shows complex patterns of genetic aberrations including MYCN amplification, deletion of chromosome 1p or 11q, and gain of chromosome 17q. The 17q gain is frequently observed in high-risk neuroblastomas,...
6.
Li M, Sanchez T, Yamase H, Hla T, Oo M, Pappalardo A, et al.
Cancer Lett
. 2009 Jan;
276(2):171-9.
PMID: 19131156
Sphingosine-1-phosphate (S1P) is an important regulator of cellular functions via interaction with its receptors S1P(1-5). To date, nothing is known about the S1P receptor expression and the effects of S1P...
7.
Rahman M, Senga T, Oo M, Hasegawa H, Biswas M, Mon N, et al.
Oncol Rep
. 2008 Mar;
19(4):975-80.
PMID: 18357384
The Src family of non-receptor protein tyrosine kinases plays a critical role in the progression of human cancers so that the development of its specific inhibitors is important as a...
8.
Oo M, Thangada S, Wu M, Liu C, Macdonald T, Lynch K, et al.
J Biol Chem
. 2007 Jan;
282(12):9082-9.
PMID: 17237497
Sphingosine 1-phosphate (S1P), a multifunctional lipid mediator, regulates lymphocyte trafficking, vascular permeability, and angiogenesis by activation of the S1P1 receptor. This receptor is activated by FTY720-P, a phosphorylated derivative of...
9.
Kohno M, Momoi M, Oo M, Paik J, Lee Y, Venkataraman K, et al.
Mol Cell Biol
. 2006 Sep;
26(19):7211-23.
PMID: 16980623
Sphingosine kinase (Sphk) enzymes are important in intracellular sphingolipid metabolism as well as in the biosynthesis of sphingosine 1-phosphate (S1P), an extracellular lipid mediator. Here, we show that Sphk1 is...
10.
Venkataraman K, Thangada S, Michaud J, Oo M, Ai Y, Lee Y, et al.
Biochem J
. 2006 Apr;
397(3):461-71.
PMID: 16623665
Sphingosine 1-phosphate (S1P), produced by Sphks (sphingosine kinases), is a multifunctional lipid mediator that regulates immune cell trafficking and vascular development. Mammals maintain a large concentration gradient of S1P between...