Muhammet Tanc
Overview
Explore the profile of Muhammet Tanc including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
328
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Recent Articles
1.
Greenwood H, Barber A, Edwards R, Tyrrell W, George M, Dos Santos S, et al.
Nat Commun
. 2024 Dec;
15(1):10484.
PMID: 39690148
Mutations in the NRF2-KEAP1 pathway are common in non-small cell lung cancer (NSCLC) and confer broad-spectrum therapeutic resistance, leading to poor outcomes. Currently, there is no means to non-invasively identify...
2.
Sambasivan K, Tyrrell W, Farooq R, Mynerich J, Edwards R, Tanc M, et al.
Npj Imaging
. 2024 Aug;
2(1):28.
PMID: 39132311
The ability to image early treatment response to radiotherapy in head and neck squamous cell carcinoma (HNSCC) will enable the identification of radioresistant tumor volumes suitable for treatment intensification. Here,...
3.
Tanc M, Filippi N, Van Rymenant Y, Grintsevich S, Pintelon I, Verschuuren M, et al.
J Med Chem
. 2024 Apr;
67(9):7068-7087.
PMID: 38656144
Fibroblast activation protein (FAP) is a very reliable biomarker for tissue remodeling. FAP has so far mainly been studied in oncology, but there is growing interest in the enzyme in...
4.
Smith L, Greenwood H, Tyrrell W, Edwards R, De Santis V, Baark F, et al.
Npj Imaging
. 2024 Jan;
1:1.
PMID: 38239706
Mouse models are invaluable tools for radiotracer development and validation. They are, however, expensive, low throughput, and are constrained by animal welfare considerations. Here, we assessed the chicken chorioallantoic membrane...
5.
Greenwood H, Edwards R, Tyrrell W, Barber A, Baark F, Tanc M, et al.
bioRxiv
. 2024 Jan;
PMID: 38168428
Mutations in the NRF2-KEAP1 pathway are common in non-small cell lung cancer (NSCLC) and confer broad-spectrum therapeutic resistance, leading to poor outcomes. The cystine/glutamate antiporter, system x, is one of...
6.
Takhsha F, Vangestel C, Tanc M, De Bruycker S, Berg M, Pintelon I, et al.
Front Oncol
. 2021 Dec;
11:750259.
PMID: 34868951
Resistance against anti-cancer therapy is one of the major challenges during treatment of multiple cancers. Gemcitabine is a standard first-line chemotherapeutic drug, yet autophagy is highly activated in the hypoxic...
7.
Van Rymenant Y, Tanc M, Van Elzen R, Bracke A, de Wever O, Augustyns K, et al.
Front Chem
. 2021 May;
9:640566.
PMID: 33996747
Fibroblast activation protein (FAP) is a proline-selective protease that belongs to the S9 family of serine proteases. It is typically highly expressed in the tumor microenvironment (TME) and especially in...
8.
Tanc M, Cleenewerck M, Kurdi A, Roelandt R, Declercq W, De Meyer G, et al.
Bioorg Chem
. 2019 Mar;
87:163-168.
PMID: 30884310
Autophagy is an intracellular degradation/recycling pathway that provides nutrients and building blocks to cellular metabolism and keeps the cytoplasm clear of obsolete proteins and organelles. During recent years, dysregulated autophagy...
9.
Nocentini A, Carta F, Tanc M, Selleri S, Supuran C, Bazzicalupi C, et al.
Chemistry
. 2018 Apr;
24(31):7840-7844.
PMID: 29603439
The reaction mechanism of the carbonic anhydrase-mediated hydrolysis of sulfocoumarins to sulfonic acids has been investigated on an enzyme cluster model using the B3LYP hybrid density functional theory (DFT) and...
10.
Aday B, Ulus R, Tanc M, Kaya M, Supuran C
Bioorg Chem
. 2018 Jan;
77:101-105.
PMID: 29353727
Herein, we report that acridine intermediates 5 were obtained from the reduction of nitro acridine derivatives 4, which were synthesized via condensation of dimedone, p-nitrobenzaldehyde with 4-amino-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)benzamide, respectively. Then acridine...