Mohit P Mathew
Overview
Explore the profile of Mohit P Mathew including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
172
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Recent Articles
1.
Saeui C, Shah S, Fernandez-Gil B, Zhang C, Agatemor C, Dammen-Brower K, et al.
ACS Chem Biol
. 2023 Jan;
18(1):151-165.
PMID: 36626752
Altered cellular metabolism is a hallmark of cancer pathogenesis and progression; for example, a near-universal feature of cancer is increased metabolic flux through the hexosamine biosynthetic pathway (HBP). This pathway...
2.
Mathew M, Donaldson J, Hanover J
Methods Mol Biol
. 2022 Mar;
2442:391-411.
PMID: 35320537
Galectin-3 is a chimeric galectin involved in diverse intracellular and extracellular functions. Galectin-3 is synthesized in the cytoplasm and then released extracellularly by a poorly understood non-canonical secretion mechanism. As...
3.
Mathew M, Abramowitz L, Donaldson J, Hanover J
J Biol Chem
. 2022 Feb;
298(3):101743.
PMID: 35183508
Endomembrane glycosylation and cytoplasmic O-GlcNAcylation each play essential roles in nutrient sensing, and characteristic changes in glycan patterns have been described in disease states such as diabetes and cancer. These...
4.
Mathew M, Donaldson J
Traffic
. 2019 Feb;
20(4):295-300.
PMID: 30706592
In contrast to clathrin-mediated endocytosis (CME) which is well characterized and understood, little is known about the regulation and machinery underlying clathrin-independent endocytosis (CIE). There is also a wide variation...
5.
Meyer R, Mathew M, Ben-Akiva E, Sunshine J, Shmueli R, Ren Q, et al.
Acta Biomater
. 2018 Apr;
72:228-238.
PMID: 29631048
Statement Of Significance: The research reported here documents the ability of non-spherical polymeric particles to be coated with lipids to form anisotropic biomimetic particles. In addition, we demonstrate that these...
6.
Mathew M, Donaldson J
J Biol Chem
. 2018 Mar;
293(19):7222-7237.
PMID: 29581232
Clathrin-independent endocytosis (CIE) is a form of endocytosis that lacks a defined cytoplasmic machinery. Here, we asked whether glycan interactions, acting from the outside, could be a part of that...
7.
Mathew M, Tan E, Labonte J, Shah S, Saeui C, Liu L, et al.
Chembiochem
. 2017 Feb;
18(13):1204-1215.
PMID: 28218815
This report describes the metabolic glycoengineering (MGE) of intracellular esterase activity in human colon cancer (LS174T) and Chinese hamster ovary (CHO) cells. In silico analysis of carboxylesterases CES1 and CES2...
8.
Badr H, AlSadek D, El-Houseini M, Saeui C, Mathew M, Yarema K, et al.
Biomaterials
. 2016 Dec;
116:158-173.
PMID: 27926828
Abnormal cell surface display of sialic acids - a family of unusual 9-carbon sugars - is widely recognized as distinguishing feature of many types of cancer. Sialoglycans, however, typically cannot...
9.
Mathew M, Tan E, Saeui C, Bovonratwet P, Sklar S, Bhattacharya R, et al.
Oncotarget
. 2016 Sep;
7(41):66491-66511.
PMID: 27613843
In prior work we reported that advanced stage, drug-resistant pancreatic cancer cells (the SW1990 line) can be sensitized to the EGFR-targeting tyrosine kinase inhibitors (TKIs) erlotinib and gefitinib by treatment...
10.
Badr H, AlSadek D, Mathew M, Li C, Djansugurova L, Yarema K, et al.
Data Brief
. 2015 Dec;
5:481-8.
PMID: 26629491
This report provides data that are specifically related to the differential sialylation of nutrient deprived breast cancer cells to sialic acid supplementation in support of the research article entitled, "Nutrient-deprived...