Mingyu Guan
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Explore the profile of Mingyu Guan including associated specialties, affiliations and a list of published articles.
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13
Citations
57
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Recent Articles
1.
Guan M, Feng Z, Jiang S, Zhou W
Entropy (Basel)
. 2025 Jan;
26(12.
PMID: 39766701
Natural disasters can severely disrupt conventional communication systems, hampering relief efforts. High-altitude tethered balloon base stations (HATBBSs) are a promising solution to communication disruptions, providing wide communication coverage in disaster-stricken...
2.
Gu X, Guan M, Jiang C, Song Q, Li X, Sun N, et al.
Chem Biodivers
. 2020 Dec;
18(2):e2000775.
PMID: 33314614
P-Glycoprotein (P-gp) overexpression is considered to be the leading cause of multidrug resistance (MDR) and failure of chemotherapy for leukemia. In this study, seventeen thiosemicarbazone-containing compounds were prepared and evaluated...
3.
Gu X, Zhang Y, Zou Y, Li X, Guan M, Zhou Q, et al.
Bioorg Med Chem
. 2020 Dec;
29:115892.
PMID: 33285406
As a continuation of our previous work, a series of new phenyl acrylamide derivatives (4Aa-g, 4Ba-t, 5 and 6a-c) were designed and synthesized as non-nucleoside anti-HBV agents. Among them, compound...
4.
Gu X, Li X, Guan M, Jiang C, Song Q, Sun N, et al.
Bioorg Med Chem Lett
. 2020 Nov;
30(24):127638.
PMID: 33132117
P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) is a major obstacle to successful chemotherapy for leukemia. In this study, a series of thiosemicarbazone-containing compounds (4a-b, 7a-q) were synthesized. Biological evaluation showed that...
5.
Qiu J, Zhou Q, Zhang Y, Guan M, Li X, Zou Y, et al.
Eur J Med Chem
. 2020 Aug;
205:112581.
PMID: 32791397
As a continuation of earlier works, a series of novel quinazolinone derivatives (5a-s) were synthesized and evaluated for their in vitro anti-HBV and anti-hepatocellular carcinoma cell (HCC) activities. Among them,...
6.
Gu X, Chen J, Zhang Y, Guan M, Li X, Zhou Q, et al.
Eur J Med Chem
. 2019 Jul;
180:62-71.
PMID: 31301564
Oxidative stress and inflammation are major causes of numerous life-threatening human diseases. In the present study, we synthesized a series of phenylacrylamide derivatives as novel anti-oxidant and anti-inflammatory agents. Biological...
7.
Gu X, Jiang Y, Chen J, Zhang Y, Guan M, Li X, et al.
Eur J Med Chem
. 2018 Nov;
162:59-69.
PMID: 30408749
Oxidative stress plays a significant role in the pathogenesis of various human diseases. In this study, a series of bifendate derivatives bearing acrylamide moiety were synthesized and evaluated as anti-oxidant...
8.
Guan M, Pang Y, Zhang J, Zhao Y
Chem Commun (Camb)
. 2016 May;
52(43):7043-6.
PMID: 27161570
The pharmacological importance of 2-quinolinone derivatives is well known. Herein, we developed an effective protocol for the synthesis of 2-quinolinone derivatives by palladium-catalyzed sequential β-C(sp(3))-H arylation and selective intramolecular C(sp(2))-H/N-H...
9.
Hu J, Guan M, Han J, Huang Z, Shi D, Zhao Y
J Org Chem
. 2015 Jul;
80(16):7896-904.
PMID: 26197216
A highly regioselective palladium-catalyzed ester-directed ortho-olefination of phenyl acetic and propionic esters with olefins via C-H bond activation has been developed. A wide variety of phenyl acetic and propionic esters...
10.
Chen C, Guan M, Zhang J, Wen Z, Zhao Y
Org Lett
. 2015 Jul;
17(15):3646-9.
PMID: 26161949
Palladium-catalyzed direct ortho-silylation of oxalyl amide-protected phenylmethanamine and phenethylamine with commercially available disilanes is reported. Germanylation products were also produced under the same reaction conditions. This protocol tolerated oxalyl amide-protected...