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Ming-Yu Gui

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Articles 10
Citations 22
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Recent Articles
1.
Asai H, Kato K, Miyasaka M, Hatsukawa K, Murakami N, Takeda N, et al.
Int Arch Allergy Immunol . 2024 May; 185(9):836-847. PMID: 38797160
Introduction: Kamebakaurin is an active constituent of both Rabdosia japonica and Rabdosia excisa, which are utilized in Chinese traditional medicine for improving symptoms in patients with allergies. We investigated the...
2.
Aoyagi Y, Tomita K, Kobayashi A, Nakamura A, Fujii Y, Yagi M, et al.
Bioorg Med Chem Lett . 2023 Jan; 82:129149. PMID: 36690039
A series of 1-O-acyl- and 1-oxo-kamebanin analogues were prepared from kamebanin, isolated from Rabdosia excisa and their cytotoxicity was assayed on HL60 promyelocytic leukemia cells and HCT116 human colon cancer...
3.
Yoshioka H, Nonogaki T, Ohnishi H, Fukuishi N, Yoshikawa M, Gui M, et al.
Biomed Res . 2018 Oct; 39(5):251-260. PMID: 30333432
The present study aimed to investigate the protective effects of kamebakaurin (KA) and 1O, 20O-diacetyl kamebakaurin (AcKA) on acetaminophen (APAP)-induced hepatotoxicity and compare the hepatoprotective mechanisms of the two chemicals....
4.
Yoshioka H, Aoyagi Y, Fukuishi N, Gui M, Jin Y, Li X, et al.
Pharmacol Rep . 2017 Jun; 69(5):903-907. PMID: 28624597
Background: Kamebakaurin (KA) is an ent-kaurane diterpenoid known to have anti-inflammatory potential. In the current study, we investigated whether pretreatment with KA could ameliorate acetaminophen (APAP)-induced hepatotoxicity by inhibiting the...
5.
Aoyagi Y, Adachi Y, Ozawa K, Yokomizo C, Gui M, Jin Y, et al.
Bioorg Med Chem . 2011 Mar; 19(7):2450-7. PMID: 21393004
A series of rabdokunmin C analogues were prepared and their inhibitory effect on NF-κB activation was assayed. One of them, 18-acetyl-12-deoxy-11,12-dehydrorabdokunmin C (16) was found to be a promising candidate...
6.
Liu G, Li X, Wang N, Zhou H, Wei W, Gui M, et al.
J Asian Nat Prod Res . 2010 Oct; 12(10):865-73. PMID: 20924900
Three new dammarane-type triterpene ginsenosides, together with six known ginsenosides, were isolated from the leaves of Panax ginseng C.A. Meyer. The new saponins were named as ginsenoside Rh₁₁, ginsenoside Rh₁₂,...
7.
Jin Y, Gui M, Lu J, Li X, Xu J
Zhongguo Zhong Yao Za Zhi . 2007 Dec; 32(18):1898-900. PMID: 18051901
Objective: To determine actinoside C in the leaves of Actinidia kolomikta with different growth periods. Method: The separation was performed at 25 degrees C on ZORBAX Extend C18 column (4.6...
8.
Aoyagi Y, Nishioka Y, Tobe F, Hasuda T, Takeya K, Gui M, et al.
Bioorg Med Chem . 2006 Jul; 14(17):5802-11. PMID: 16828562
1-O-Monoacyl, 12-O-monoacyl, 1-,12-O-diacyl, and 11,12-dehydrated excisanin A 7,14-acetonides were synthesized from excisanin A isolated from Rabdosia excisa. The structure and cytotoxic activity relationships (SAR) of the natural parent ent-kaurene diterpenes...
9.
Li X, Gui M, Zheng Y, Jin Y, Zhang H
Zhongguo Zhong Yao Za Zhi . 2006 May; 31(5):386-8. PMID: 16711421
Objective: To determine 20(S)-ginsengnoside Rh2 in the hydrolysis product of saponins from leaves of Panax qinquefolium. Method: The separation was performed on ZORBAX EXEND C18 column (4.6 mm x 250...
10.
Gui M, Aoyagi Y, Jin Y, Li X, Hasuda T, Takeya K
J Nat Prod . 2004 Mar; 67(3):373-6. PMID: 15043413
A novel 14,20-epoxy-ent-kaurene diterpenoid, excisanin H (1), and three new ent-kaurene diterpenoids, 2-4, were isolated from aerial parts of Rabdosia excisa along with eight known ent-kaurene diterpenoids, 5-12. The structural...