Mikko Ora
Overview
Explore the profile of Mikko Ora including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
60
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rosenqvist P, Saari V, Ora M, Molina A, Horvath A, Virta P
J Org Chem
. 2024 Sep;
89(18):13005-13015.
PMID: 39250641
Solubility of the growing oligonucleotide-soluble support constructs in the liquid phase oligonucleotide synthesis (LPOS) is a critical parameter, which affects coupling efficiency, purity, and recovery of the growing oligonucleotides during...
2.
Saleh L, Ora M, Lonnberg T
J Inorg Biochem
. 2023 Jul;
247:112331.
PMID: 37480764
Two oligonucleotide conjugates sharing the same sequence but incorporating a different 5'-terminal organometallic moiety were synthesized, by either direct mercuration in solution or oximation with an organomercury aldehyde on solid...
3.
Rosenqvist P, Saari V, Pajuniemi E, Molina A, Ora M, Horvath A, et al.
J Org Chem
. 2023 Jul;
88(14):10156-10163.
PMID: 37428953
5'--(2-Methoxyisopropyl) (MIP)-protected 2'-deoxynucleosides as chiral P(V)-building blocks, based on the limonene-derived oxathiaphospholane sulfide, were synthesized and used for the assembly of di-, tri-, and tetranucleotide phosphorothioates on a tetrapodal pentaerythritol-derived...
4.
Hassan N, Sabt A, El-Attar M, Ora M, Bekhit A, Amagase K, et al.
Eur J Med Chem
. 2023 Apr;
253:115333.
PMID: 37031526
In accordance with WHO statistics, leishmaniasis is one of the top neglected tropical diseases, affecting around 700 000 to one million people per year. To that end, a new series...
5.
Saleh L, Ora M, Lonnberg T
Chembiochem
. 2021 Jan;
22(10):1761-1764.
PMID: 33448598
A water-soluble arylmercury complex has been synthesized, and its ability to catalyze the cleavage of the phosphodiester linkage of the RNA model compound adenylyl-3',5'-(2',3'-O-methyleneadenosine) has been assessed over a pH...
6.
Siddiqui F, Alam C, Rosenqvist P, Ora M, Sabt A, Manoharan G, et al.
ACS Omega
. 2020 Jan;
5(1):832-842.
PMID: 31956834
The trafficking chaperone PDE6D (also referred to as PDEδ) has been nominated as a surrogate target for K-Ras4B (hereafter K-Ras). Arl2-assisted unloading of K-Ras from PDE6D in the perinuclear area...
7.
Kiuru E, Malmikare S, Ora M
Chem Biodivers
. 2017 May;
14(9).
PMID: 28557349
Protected dinucleoside-2',5'-monophosphate has been prepared to develop a prodrug strategy for 2-5A. The removal of enzymatically and thermally labile 4-(acetylthio)-2-(ethoxycarbonyl)-3-oxo-2-methylbutyl phosphate protecting group and enzymatically labile 3'-O-pivaloyloxymethyl group was followed...
8.
Kiuru E, Ahmed Z, Lonnberg H, Beigelman L, Ora M
J Org Chem
. 2013 Jan;
78(3):950-9.
PMID: 23272806
Five different 2,2-disubstituted 4-acylthio-3-oxobutyl groups have been introduced as esterase-labile phosphodiester protecting groups that additionally are thermolabile. The phosphotriesters 1-3 were prepared to determine the rate of the enzymatic and...
9.
Kiuru E, Ora M, Beigelman L, Blatt L, Lonnberg H
Chem Biodivers
. 2012 Apr;
9(4):669-88.
PMID: 22492487
Fully protected pA2'p5'A2'p5'A trimers 1a and 1b have been prepared as prodrug candidates for a short 2'-5' oligoadenylate, 2-5A, and its 3'-O-Me analog, respectively. The kinetics of hog liver carboxyesterase...
10.
Kiuru E, Ora M, Beigelman L, Blatt L, Lonnberg H
Chem Biodivers
. 2011 Feb;
8(2):266-86.
PMID: 21337500
As a first step towards a viable prodrug strategy for short oligoribonucleotides, such as 2-5A and its congeners, adenylyl-2',5'-adenosines bearing a 3-(acetyloxy)-2,2-bis(ethoxycarbonyl)propyl group at the phosphate moiety, and an (acetyloxy)methyl-...